Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PHA55_RS14420 Genome accession   NZ_CP116044
Coordinates   2946544..2947200 (-) Length   218 a.a.
NCBI ID   WP_260589808.1    Uniprot ID   -
Organism   Escherichia coli strain STEC1575     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2941544..2952200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA55_RS14390 (PHA55_14385) yecA 2942795..2943460 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  PHA55_RS14410 (PHA55_14405) pgsA 2944110..2944658 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PHA55_RS14415 (PHA55_14410) uvrC 2944715..2946547 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PHA55_RS14420 (PHA55_14415) letA 2946544..2947200 (-) 657 WP_260589808.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PHA55_RS24710 - 2947342..2947413 (+) 72 Protein_2814 transcriptional regulator -
  PHA55_RS14425 (PHA55_14420) yecU 2947496..2947672 (+) 177 WP_000590347.1 protein YecU -
  PHA55_RS14430 (PHA55_14425) yecF 2947659..2947883 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PHA55_RS14435 (PHA55_14430) sdiA 2947950..2948672 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  PHA55_RS14440 (PHA55_14435) tcyN 2948902..2949654 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PHA55_RS14445 (PHA55_14440) tcyL 2949651..2950319 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PHA55_RS14450 (PHA55_14445) dcyD 2950334..2951320 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23906.68 Da        Isoelectric Point: 6.9614

>NTDB_id=707110 PHA55_RS14420 WP_260589808.1 2946544..2947200(-) (letA) [Escherichia coli strain STEC1575]
MINVLLVDDHELVRAGIRRILEDIKGIKVIGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=707110 PHA55_RS14420 WP_260589808.1 2946544..2947200(-) (letA) [Escherichia coli strain STEC1575]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCATCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482