Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PGH49_RS00155 Genome accession   NZ_CP116035
Coordinates   28551..29141 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain FAH     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23551..34141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PGH49_RS00120 (PGH49_00120) yidG 23843..24205 (+) 363 WP_001113432.1 DUF202 domain-containing protein -
  PGH49_RS00125 (PGH49_00125) yidF 24202..24699 (+) 498 WP_000148045.1 radical SAM protein -
  PGH49_RS00130 (PGH49_00130) emrD 24707..25891 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  PGH49_RS00135 (PGH49_00135) ysdE 25973..26047 (+) 75 WP_211180519.1 protein YsdE -
  PGH49_RS00140 (PGH49_00140) ivbL 26292..26390 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  PGH49_RS00145 (PGH49_00145) ilvB 26496..28184 (+) 1689 WP_000168476.1 acetolactate synthase large subunit -
  PGH49_RS00150 (PGH49_00150) ilvN 28188..28478 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PGH49_RS00155 (PGH49_00155) letA 28551..29141 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PGH49_RS00160 (PGH49_00160) uhpB 29141..30643 (+) 1503 WP_001314238.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PGH49_RS00165 (PGH49_00165) uhpC 30653..31972 (+) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PGH49_RS00170 (PGH49_00170) uhpT 32110..33501 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=706979 PGH49_RS00155 WP_000633668.1 28551..29141(+) (letA) [Escherichia coli strain FAH]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=706979 PGH49_RS00155 WP_000633668.1 28551..29141(+) (letA) [Escherichia coli strain FAH]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACATGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378