Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIB26_RS00390 Genome accession   NZ_CP115968
Coordinates   76325..76915 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B-DidR     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 71325..81915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIB26_RS00355 yidF 71441..71938 (+) 498 WP_000148063.1 radical SAM protein -
  PIB26_RS00360 emrD 71946..73130 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PIB26_RS00365 ysdE 73212..73286 (+) 75 WP_211180519.1 protein YsdE -
  PIB26_RS00370 tisB 73410..73499 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PIB26_RS00375 ivbL 74064..74162 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PIB26_RS00380 ilvB 74268..75956 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  PIB26_RS00385 ilvN 75960..76250 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PIB26_RS00390 letA 76325..76915 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PIB26_RS00395 uhpB 76915..78417 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIB26_RS00400 uhpC 78427..79746 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIB26_RS00405 uhpT 79884..81275 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=706547 PIB26_RS00390 WP_000633668.1 76325..76915(+) (letA) [Escherichia coli strain B-DidR]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=706547 PIB26_RS00390 WP_000633668.1 76325..76915(+) (letA) [Escherichia coli strain B-DidR]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGTCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378