Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NKZ64_RS04500 Genome accession   NZ_CP100338
Coordinates   881141..882520 (+) Length   459 a.a.
NCBI ID   WP_002935290.1    Uniprot ID   A0A0Z8I1B6
Organism   Streptococcus suis strain STC80     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 876141..887520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKZ64_RS04470 (NKZ64_04470) pstA 876567..877454 (+) 888 WP_002937616.1 phosphate ABC transporter permease PstA -
  NKZ64_RS04475 (NKZ64_04475) pstB 877479..878282 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  NKZ64_RS04480 (NKZ64_04480) pstB 878294..879052 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  NKZ64_RS04485 (NKZ64_04485) phoU 879081..879737 (+) 657 WP_012028219.1 phosphate signaling complex protein PhoU -
  NKZ64_RS11285 - 879903..880037 (+) 135 WP_255304292.1 hypothetical protein -
  NKZ64_RS04490 (NKZ64_04490) - 880095..880283 (+) 189 WP_226313374.1 hypothetical protein -
  NKZ64_RS04495 (NKZ64_04495) ciaR 880477..881148 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  NKZ64_RS04500 (NKZ64_04500) ciaH 881141..882520 (+) 1380 WP_002935290.1 cell wall metabolism sensor histidine kinase WalK Regulator
  NKZ64_RS04505 (NKZ64_04505) - 882844..884073 (+) 1230 WP_024417479.1 transglutaminase domain-containing protein -
  NKZ64_RS04510 (NKZ64_04510) rpsT 884335..884583 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  NKZ64_RS04515 (NKZ64_04515) coaA 884642..885562 (-) 921 WP_024381359.1 type I pantothenate kinase -
  NKZ64_RS04520 (NKZ64_04520) - 885671..886261 (+) 591 WP_254369418.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51921.60 Da        Isoelectric Point: 6.8879

>NTDB_id=704607 NKZ64_RS04500 WP_002935290.1 881141..882520(+) (ciaH) [Streptococcus suis strain STC80]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSTPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQMAANIKDKLVCFTVIDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=704607 NKZ64_RS04500 WP_002935290.1 881141..882520(+) (ciaH) [Streptococcus suis strain STC80]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCACGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGGTTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGGTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCAGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAAGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATGGCAGCTAATATCAAGGATAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGCC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8I1B6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

48.791

99.129

0.484