Detailed information NTG0704370

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: NKZ80_RS00815
• Genome accession: NZ_CP100330
• Coordinates: 128910..129344 (+)
• Length: 144 a.a.
• NCBI ID: WP_063725150.1
• Uniprot ID: -
• Organism: Streptococcus suis strain STC85
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 123910..134344

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ80_RS00780 (NKZ80_00780)	-	124652..125017 (+)	366	WP_024417409.1	DUF1033 family protein	-
NKZ80_RS00785 (NKZ80_00785)	-	125052..126002 (-)	951	WP_024417410.1	S66 peptidase family protein	-
NKZ80_RS00790 (NKZ80_00790)	comYA	126088..127038 (+)	951	WP_024417411.1	competence type IV pilus ATPase ComGA	Machinery gene
NKZ80_RS00795 (NKZ80_00795)	comYB	126950..127987 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
NKZ80_RS00800 (NKZ80_00800)	comYC	127989..128270 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
NKZ80_RS00805 (NKZ80_00805)	comGD	128251..128658 (+)	408	WP_024387070.1	competence type IV pilus minor pilin ComGD	-
NKZ80_RS00810 (NKZ80_00810)	comYE	128630..128923 (+)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
NKZ80_RS00815 (NKZ80_00815)	comGF/cglF	128910..129344 (+)	435	WP_063725150.1	competence type IV pilus minor pilin ComGF	Machinery gene
NKZ80_RS00820 (NKZ80_00820)	comGG	129322..129732 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
NKZ80_RS00825 (NKZ80_00825)	comYH	129789..130742 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
NKZ80_RS00830 (NKZ80_00830)	-	130792..131979 (+)	1188	WP_014637319.1	acetate kinase	-
NKZ80_RS00835 (NKZ80_00835)	-	132294..132845 (+)	552	WP_024417413.1	folate family ECF transporter S component	-
NKZ80_RS00840 (NKZ80_00840)	-	132901..134157 (+)	1257	WP_024417414.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16420.77 Da
• Isoelectric Point: 6.9834

>NTDB_id=704370 NKZ80_RS00815 WP_063725150.1 128910..129344(+) (comGF/cglF) [Streptococcus suis strain STC85]
MLKSKIPAFTLLECLVALVILSGSLLVFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVDKDG
QALAFGKSRSDDFRKTNDRGQGYQPMLYQVDSAAISQEKQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=704370 NKZ80_RS00815 WP_063725150.1 128910..129344(+) (comGF/cglF) [Streptococcus suis strain STC85]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCCTTAGTCATCCTTTCAGGTAGTCTTCTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCGATAAGGATGGA
CAAGCATTAGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGTTACCAGCCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAAGCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae Rx1	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae D39	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae R6	53.901	97.917	0.528
comGF/cglF	Streptococcus mitis NCTC 12261	54.478	93.056	0.507
comYF	Streptococcus mutans UA140	50	100	0.5
comYF	Streptococcus mutans UA159	49.306	100	0.493
comGF/cglF	Streptococcus mitis SK321	51.493	93.056	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	47.518	97.917	0.465