Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PCS81_RS09980 Genome accession   NZ_CP115342
Coordinates   2081549..2082205 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CUVET21-1780     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2076549..2087205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCS81_RS09950 (PCS81_09945) dcyD 2077429..2078415 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  PCS81_RS09955 (PCS81_09950) tcyL 2078430..2079098 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PCS81_RS09960 (PCS81_09955) tcyN 2079095..2079847 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PCS81_RS09965 (PCS81_09960) sdiA 2080077..2080799 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  PCS81_RS09970 (PCS81_09965) yecF 2080866..2081090 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PCS81_RS09975 (PCS81_09970) yecU 2081077..2081253 (-) 177 WP_001307856.1 protein YecU -
  PCS81_RS09980 (PCS81_09975) letA 2081549..2082205 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PCS81_RS09985 (PCS81_09980) uvrC 2082202..2084034 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PCS81_RS09990 (PCS81_09985) pgsA 2084091..2084639 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PCS81_RS10010 (PCS81_10005) - 2085337..2085978 (-) 642 Protein_1950 hypothetical protein -
  PCS81_RS10015 (PCS81_10010) - 2086051..2087139 (+) 1089 Protein_1951 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=703445 PCS81_RS09980 WP_000611328.1 2081549..2082205(+) (letA) [Escherichia coli strain CUVET21-1780]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=703445 PCS81_RS09980 WP_000611328.1 2081549..2082205(+) (letA) [Escherichia coli strain CUVET21-1780]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482