Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PCS83_RS13360 Genome accession   NZ_CP115320
Coordinates   2677266..2677922 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CUVET18-565     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2672266..2682922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCS83_RS13330 (PCS83_13285) yecA 2673518..2674183 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  PCS83_RS13350 (PCS83_13305) pgsA 2674832..2675380 (-) 549 WP_001538881.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PCS83_RS13355 (PCS83_13310) uvrC 2675437..2677269 (-) 1833 WP_001773939.1 excinuclease ABC subunit UvrC Machinery gene
  PCS83_RS13360 (PCS83_13315) letA 2677266..2677922 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PCS83_RS13365 (PCS83_13320) yecU 2678218..2678394 (+) 177 WP_001307856.1 protein YecU -
  PCS83_RS13370 (PCS83_13325) yecF 2678381..2678605 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PCS83_RS13375 (PCS83_13330) sdiA 2678673..2679395 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  PCS83_RS13380 (PCS83_13335) tcyN 2679625..2680377 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PCS83_RS13385 (PCS83_13340) tcyL 2680374..2681042 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PCS83_RS13390 (PCS83_13345) dcyD 2681057..2682043 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=703191 PCS83_RS13360 WP_000611328.1 2677266..2677922(-) (letA) [Escherichia coli strain CUVET18-565]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=703191 PCS83_RS13360 WP_000611328.1 2677266..2677922(-) (letA) [Escherichia coli strain CUVET18-565]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTTAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482