Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EL290_RS08145 Genome accession   NZ_AP018585
Coordinates   1723977..1724849 (-) Length   290 a.a.
NCBI ID   WP_037541402.1    Uniprot ID   -
Organism   Staphylococcus caprae strain JMUB145     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1681624..1760000 1723977..1724849 within 0


Gene organization within MGE regions


Location: 1681624..1760000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL290_RS07970 (JMUB145_1611) pgsA 1682463..1683044 (-) 582 WP_126493778.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EL290_RS07975 (JMUB145_1612) - 1683076..1683468 (-) 393 WP_002442599.1 helix-turn-helix domain-containing protein -
  EL290_RS07980 (JMUB145_1613) - 1683487..1684314 (-) 828 WP_002442598.1 YmfK family protein -
  EL290_RS07985 (JMUB145_1614) ymfI 1684499..1685203 (-) 705 WP_002442596.1 elongation factor P 5-aminopentanone reductase -
  EL290_RS07990 (JMUB145_1615) yfmH 1685203..1686489 (-) 1287 WP_002442594.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  EL290_RS07995 (JMUB145_1616) yfmF 1686489..1687754 (-) 1266 WP_037541551.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  EL290_RS08000 (JMUB145_1617) - 1687801..1688511 (-) 711 WP_002442591.1 GntR family transcriptional regulator -
  EL290_RS12875 - 1688514..1689965 (-) 1452 Protein_1536 DNA translocase FtsK -
  EL290_RS12880 - 1690064..1690925 (-) 862 Protein_1537 DNA translocase FtsK 4TM domain-containing protein -
  EL290_RS08010 (JMUB145_1619) rnjB 1691190..1692863 (-) 1674 WP_037541414.1 ribonuclease J2 -
  EL290_RS08020 (JMUB145_1620) pnp 1693104..1695203 (-) 2100 WP_049402112.1 polyribonucleotide nucleotidyltransferase -
  EL290_RS08025 (JMUB145_1621) rpsO 1695520..1695789 (-) 270 WP_002442583.1 30S ribosomal protein S15 -
  EL290_RS08030 (JMUB145_1622) ribF 1696050..1697021 (-) 972 WP_002442581.1 riboflavin biosynthesis protein RibF -
  EL290_RS08035 (JMUB145_1623) truB 1697037..1697954 (-) 918 WP_002442577.1 tRNA pseudouridine(55) synthase TruB -
  EL290_RS08040 (JMUB145_1624) rbfA 1698102..1698452 (-) 351 WP_037541413.1 30S ribosome-binding factor RbfA -
  EL290_RS08045 (JMUB145_1625) infB 1698614..1700779 (-) 2166 WP_044466282.1 translation initiation factor IF-2 -
  EL290_RS08050 (JMUB145_1626) - 1700784..1701101 (-) 318 WP_002442572.1 L7Ae/L30e/S12e/Gadd45 family ribosomal protein -
  EL290_RS08055 (JMUB145_1627) rnpM 1701098..1701382 (-) 285 WP_002442571.1 RNase P modulator RnpM -
  EL290_RS08060 (JMUB145_1628) nusA 1701399..1702610 (-) 1212 WP_002442570.1 transcription termination factor NusA -
  EL290_RS08065 (JMUB145_1629) rimP 1702631..1703098 (-) 468 WP_037541410.1 ribosome maturation factor RimP -
  EL290_RS08070 (JMUB145_1630) - 1703280..1707590 (-) 4311 WP_095323372.1 PolC-type DNA polymerase III -
  EL290_RS08075 (JMUB145_1631) - 1707843..1709546 (-) 1704 WP_002442566.1 proline--tRNA ligase -
  EL290_RS08080 (JMUB145_1632) rseP 1709566..1710852 (-) 1287 WP_002442564.1 RIP metalloprotease RseP -
  EL290_RS08085 (JMUB145_1633) - 1711093..1711875 (-) 783 WP_002442562.1 phosphatidate cytidylyltransferase -
  EL290_RS08090 (JMUB145_1634) - 1711879..1712649 (-) 771 WP_037541408.1 isoprenyl transferase -
  EL290_RS08095 (JMUB145_1635) frr 1712933..1713487 (-) 555 WP_002442559.1 ribosome recycling factor -
  EL290_RS08100 (JMUB145_1636) pyrH 1713504..1714226 (-) 723 WP_002436299.1 UMP kinase -
  EL290_RS08105 (JMUB145_1637) tsf 1714364..1715242 (-) 879 WP_002442557.1 translation elongation factor Ts -
  EL290_RS08110 (JMUB145_1638) rpsB 1715396..1716184 (-) 789 WP_002442555.1 30S ribosomal protein S2 -
  EL290_RS08115 (JMUB145_1639) codY 1716436..1717209 (-) 774 WP_037541406.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  EL290_RS08120 (JMUB145_1640) hslU 1717232..1718635 (-) 1404 WP_002442550.1 ATP-dependent protease ATPase subunit HslU -
  EL290_RS08125 (JMUB145_1641) hslV 1718720..1719262 (-) 543 WP_002442548.1 ATP-dependent protease subunit HslV -
  EL290_RS08130 (JMUB145_1642) xerC 1719266..1720156 (-) 891 WP_037541405.1 tyrosine recombinase XerC -
  EL290_RS08135 (JMUB145_1643) trmFO 1720390..1721697 (-) 1308 WP_037541403.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EL290_RS08140 (JMUB145_1644) topA 1721724..1723799 (-) 2076 WP_167495587.1 type I DNA topoisomerase -
  EL290_RS08145 (JMUB145_1645) dprA 1723977..1724849 (-) 873 WP_037541402.1 DNA-processing protein DprA Machinery gene
  EL290_RS08150 (JMUB145_1646) sucD 1725113..1726021 (-) 909 WP_002442537.1 succinate--CoA ligase subunit alpha -
  EL290_RS08155 (JMUB145_1647) sucC 1726043..1727209 (-) 1167 WP_002442536.1 ADP-forming succinate--CoA ligase subunit beta -
  EL290_RS08160 (JMUB145_1649) - 1727317..1728087 (-) 771 WP_002442534.1 ribonuclease HII -
  EL290_RS08165 (JMUB145_1650) ylqF 1728071..1728955 (-) 885 WP_037541400.1 ribosome biogenesis GTPase YlqF -
  EL290_RS08170 (JMUB145_1651) - 1729232..1731832 (+) 2601 WP_126493780.1 YfhO family protein -
  EL290_RS08175 (JMUB145_1652) - 1731825..1734434 (+) 2610 WP_126493781.1 YfhO family protein -
  EL290_RS08180 (JMUB145_1653) rplS 1734620..1734970 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  EL290_RS08185 (JMUB145_1654) trmD 1735075..1735812 (-) 738 WP_002442526.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EL290_RS08190 (JMUB145_1655) rimM 1735812..1736315 (-) 504 WP_002442524.1 ribosome maturation factor RimM -
  EL290_RS08195 (JMUB145_1656) rpsP 1736439..1736714 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  EL290_RS08200 (JMUB145_1657) ffh 1736930..1738297 (-) 1368 WP_126493782.1 signal recognition particle protein -
  EL290_RS08205 (JMUB145_1658) - 1738329..1738661 (-) 333 WP_002442519.1 putative DNA-binding protein -
  EL290_RS08210 (JMUB145_1659) ftsY 1738648..1739904 (-) 1257 WP_002442517.1 signal recognition particle-docking protein FtsY -
  EL290_RS08215 (JMUB145_1660) smc 1739901..1743470 (-) 3570 WP_044466284.1 chromosome segregation protein SMC -
  EL290_RS08220 (JMUB145_1661) rnc 1743569..1744315 (-) 747 WP_002442511.1 ribonuclease III -
  EL290_RS08225 (JMUB145_1662) - 1744435..1744668 (-) 234 WP_001830184.1 acyl carrier protein -
  EL290_RS08230 (JMUB145_1663) fabG 1745093..1745827 (-) 735 WP_037541397.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EL290_RS08235 (JMUB145_1664) fabD 1745820..1746746 (-) 927 WP_037541396.1 ACP S-malonyltransferase -
  EL290_RS08240 (JMUB145_1665) plsX 1746739..1747725 (-) 987 WP_037541395.1 phosphate acyltransferase PlsX -
  EL290_RS08245 (JMUB145_1666) fapR 1747718..1748287 (-) 570 WP_044466285.1 transcription factor FapR -
  EL290_RS08250 (JMUB145_1667) recG 1748630..1750678 (-) 2049 WP_002442500.1 ATP-dependent DNA helicase RecG -
  EL290_RS12805 - 1750901..1751170 (-) 270 WP_232019016.1 excalibur calcium-binding domain-containing protein -
  EL290_RS08255 (JMUB145_1668) - 1751150..1751755 (-) 606 Protein_1587 thermonuclease family protein -
  EL290_RS08260 (JMUB145_1669) - 1752032..1753099 (-) 1068 WP_037541391.1 Leu/Phe/Val dehydrogenase -
  EL290_RS08265 (JMUB145_1670) fakA 1753336..1754994 (-) 1659 WP_126493783.1 fatty acid kinase catalytic subunit FakA -
  EL290_RS08270 (JMUB145_1671) - 1755009..1755383 (-) 375 WP_037541388.1 Asp23/Gls24 family envelope stress response protein -
  EL290_RS08275 (JMUB145_1672) rpmB 1755762..1755950 (+) 189 WP_002435210.1 50S ribosomal protein L28 -
  EL290_RS08280 (JMUB145_1673) - 1756222..1756857 (-) 636 WP_002442491.1 thiamine diphosphokinase -
  EL290_RS08285 (JMUB145_1674) rpe 1756862..1757506 (-) 645 WP_002442490.1 ribulose-phosphate 3-epimerase -
  EL290_RS08290 (JMUB145_1675) rsgA 1757507..1758382 (-) 876 WP_002442489.1 ribosome small subunit-dependent GTPase A -
  EL290_RS08295 (JMUB145_1676) - 1758558..1759745 (+) 1188 WP_002442488.1 CynX/NimT family MFS transporter -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33821.84 Da        Isoelectric Point: 8.8335

>NTDB_id=70143 EL290_RS08145 WP_037541402.1 1723977..1724849(-) (dprA) [Staphylococcus caprae strain JMUB145]
MIQHTLLKLYWANFTTTQVHQIIDFYPDFSLENEQTRMDIIKDWVLKQNSHALQRKLDQFKMLKTEYLYNYMKRIKLKYV
TYYDKDYPLLLKEIYHFPYVIFYKGTKQLFNQPHTLAVIGSRKSTSYTTQALEYLFPSFQQIQMTIISGLAYGADSVAHQ
VALKYHLPTIGVLGFGHDYHYPQSTYQLRDKIEKSGLVLSEYPPHSAISKYKFPERNRLISGLSRGLLITEAEEKSGSQI
TVDCALEQNRNVYVLPGSMFNQMTKGNLLRLEEGAQVVLDESSILTDYTF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=70143 EL290_RS08145 WP_037541402.1 1723977..1724849(-) (dprA) [Staphylococcus caprae strain JMUB145]
TTGATTCAACACACTTTATTAAAACTTTATTGGGCTAATTTCACTACAACGCAAGTACATCAAATCATTGATTTCTATCC
TGACTTTTCCTTGGAAAATGAACAAACAAGAATGGATATTATAAAAGATTGGGTATTAAAACAAAATTCCCACGCATTGC
AAAGAAAACTTGATCAATTTAAAATGCTAAAAACTGAGTATTTATACAACTATATGAAACGTATAAAACTAAAATATGTG
ACTTACTATGACAAAGATTATCCTTTACTTCTCAAAGAAATCTATCATTTTCCATACGTAATTTTTTATAAAGGAACCAA
ACAATTGTTTAATCAACCTCATACATTAGCTGTAATCGGCTCTCGTAAATCTACTTCATATACGACACAAGCTTTAGAGT
ATCTTTTTCCTTCATTTCAACAAATTCAAATGACTATAATTTCTGGTTTAGCATACGGCGCAGATAGTGTAGCGCATCAA
GTCGCTCTCAAATACCATTTACCCACCATAGGAGTTCTGGGATTCGGTCATGATTATCACTATCCTCAATCCACATATCA
ATTAAGAGATAAGATTGAAAAAAGTGGATTAGTATTAAGTGAATATCCTCCTCATTCAGCAATCAGTAAGTATAAATTTC
CAGAAAGAAATAGATTGATAAGTGGGCTTTCACGTGGCTTACTTATTACGGAAGCTGAAGAAAAAAGTGGCAGTCAAATT
ACTGTTGATTGTGCTTTAGAACAAAATCGAAATGTGTATGTGTTACCTGGATCCATGTTTAATCAAATGACAAAGGGAAA
TTTACTTAGATTAGAAGAAGGTGCTCAAGTCGTATTAGATGAAAGCAGCATTTTAACAGACTATACATTCTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

57.292

99.31

0.569
  dprA Staphylococcus aureus N315

57.292

99.31

0.569
  dprA Streptococcus mutans UA159

36.552

100

0.366

Multiple sequence alignment