Detailed information NTG0701178

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: NEE09_RS01540
• Genome accession: NZ_CP099641
• Coordinates: 288654..289664 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain ATCC 700671
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 283654..294664

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NEE09_RS01510	-	284525..284731 (+)	207	Protein_265	hypothetical protein	-
NEE09_RS01515	-	284728..284922 (+)	195	WP_000715302.1	hypothetical protein	-
NEE09_RS01520	-	284909..285793 (+)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
NEE09_RS01525	-	285795..286532 (+)	738	WP_000832916.1	ABC transporter permease	-
NEE09_RS01530	-	286532..287629 (+)	1098	WP_000893503.1	sensor histidine kinase	-
NEE09_RS01535	-	287630..288229 (+)	600	WP_000866703.1	response regulator transcription factor	-
NEE09_RS01540	ccpA	288654..289664 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
NEE09_RS01545	-	289728..290111 (+)	384	WP_001092022.1	hypothetical protein	-
NEE09_RS01550	-	290140..291102 (-)	963	WP_001124786.1	asparaginase	-
NEE09_RS01555	-	291168..292556 (+)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
NEE09_RS01560	-	292591..293043 (-)	453	WP_000079148.1	universal stress protein	-
NEE09_RS01565	-	293205..293499 (+)	295	Protein_276	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=701178 NEE09_RS01540 WP_000990607.1 288654..289664(+) (ccpA) [Streptococcus pneumoniae strain ATCC 700671]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=701178 NEE09_RS01540 WP_000990607.1 288654..289664(+) (ccpA) [Streptococcus pneumoniae strain ATCC 700671]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568