Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SA58113_RS09625 Genome accession   NZ_AP018562
Coordinates   1955504..1956133 (-) Length   209 a.a.
NCBI ID   WP_126495162.1    Uniprot ID   -
Organism   Staphylococcus argenteus strain 58113     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1950504..1961133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA58113_RS09595 (SA58113_1850) - 1950912..1951442 (-) 531 WP_000184380.1 acyl-CoA thioesterase -
  SA58113_RS09600 (SA58113_1851) - 1951534..1952781 (-) 1248 WP_000656301.1 aminopeptidase -
  SA58113_RS09605 (SA58113_1852) - 1952793..1952993 (-) 201 WP_000180459.1 DUF1128 family protein -
  SA58113_RS09610 (SA58113_1853) - 1953140..1953604 (+) 465 WP_000228669.1 low molecular weight protein-tyrosine-phosphatase -
  SA58113_RS09615 (SA58113_1854) - 1953611..1953886 (+) 276 WP_000428174.1 YtxH domain-containing protein -
  SA58113_RS09620 (SA58113_1855) - 1954165..1955388 (+) 1224 WP_000037065.1 YihY/virulence factor BrkB family protein -
  SA58113_RS09625 (SA58113_1856) vraR 1955504..1956133 (-) 630 WP_126495162.1 two-component system response regulator VraR Regulator
  SA58113_RS09630 (SA58113_1857) vraS 1956123..1957166 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  SA58113_RS09635 (SA58113_1858) liaF 1957163..1957864 (-) 702 WP_031788217.1 cell wall-active antibiotics response protein LiaF -
  SA58113_RS09640 (SA58113_1859) - 1957879..1958265 (-) 387 WP_001110170.1 hypothetical protein -
  SA58113_RS09645 (SA58113_1860) map 1958486..1959244 (-) 759 WP_031788218.1 type I methionyl aminopeptidase -
  SA58113_RS09650 (SA58113_1861) - 1959775..1960761 (+) 987 WP_031788370.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23545.34 Da        Isoelectric Point: 5.3889

>NTDB_id=70108 SA58113_RS09625 WP_126495162.1 1955504..1956133(-) (vraR) [Staphylococcus argenteus strain 58113]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSKGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQVVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=70108 SA58113_RS09625 WP_126495162.1 1955504..1956133(-) (vraR) [Staphylococcus argenteus strain 58113]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTAGGTGAGGGGGCTTCAGGTAAAGAAGCAATCGCTAAAGCCCATGAGCTAAAACCTGATTTGATTTTAA
TGGATTTGCTTATGGATGATATGGATGGTGTAGAAGCGACTACTCAAATTAAAAAAGATTTACCACAAATTAAAGTATTA
ATGCTAACAAGTTTTATTGAAGATAAAGAGGTATATCGTGCCTTAGATGCAGGTGTTGATAGCTATATTTTAAAAACAAC
GAGTGCAAAAGATATTGCTGATGCAGTTCGTAAAACATCTAAAGGTGAATCTGTATTTGAACCTGAAGTATTAGTAAAAA
TGCGTAACCGTATGAAAAAACGTGCTGAGTTATATGAAATGTTAACGGAACGTGAAATGGAAATATTATTATTAATTGCC
AAAGGTTATTCAAATCAAGAGATTGCAAGTGCATCTCATATTACAATTAAAACAGTTAAGACACATGTAAGTAATATTTT
AAGTAAGTTAGAAGTACAAGATAGAACACAAGTCGTTATTTATGCATTCCAACATAATTTAATTCAGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

98.565

100

0.986
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment