Detailed information NTG0070109

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SA58113_RS09630
• Genome accession: NZ_AP018562
• Coordinates: 1956123..1957166 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain 58113
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1951123..1962166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA58113_RS09600 (SA58113_1851)	-	1951534..1952781 (-)	1248	WP_000656301.1	aminopeptidase	-
SA58113_RS09605 (SA58113_1852)	-	1952793..1952993 (-)	201	WP_000180459.1	DUF1128 family protein	-
SA58113_RS09610 (SA58113_1853)	-	1953140..1953604 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
SA58113_RS09615 (SA58113_1854)	-	1953611..1953886 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
SA58113_RS09620 (SA58113_1855)	-	1954165..1955388 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
SA58113_RS09625 (SA58113_1856)	vraR	1955504..1956133 (-)	630	WP_126495162.1	two-component system response regulator VraR	Regulator
SA58113_RS09630 (SA58113_1857)	vraS	1956123..1957166 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SA58113_RS09635 (SA58113_1858)	liaF	1957163..1957864 (-)	702	WP_031788217.1	cell wall-active antibiotics response protein LiaF	-
SA58113_RS09640 (SA58113_1859)	-	1957879..1958265 (-)	387	WP_001110170.1	hypothetical protein	-
SA58113_RS09645 (SA58113_1860)	map	1958486..1959244 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
SA58113_RS09650 (SA58113_1861)	-	1959775..1960761 (+)	987	WP_031788370.1	FUSC family protein	-
SA58113_RS09655 (SA58113_1862)	-	1961393..1962115 (-)	723	WP_031787877.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=70109 SA58113_RS09630 WP_001017131.1 1956123..1957166(-) (vraS) [Staphylococcus argenteus strain 58113]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=70109 SA58113_RS09630 WP_001017131.1 1956123..1957166(-) (vraS) [Staphylococcus argenteus strain 58113]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTTTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAAGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1