Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   HPTL_RS02785 Genome accession   NZ_AP018558
Coordinates   569902..571221 (-) Length   439 a.a.
NCBI ID   WP_119334614.1    Uniprot ID   A0A2Z6DWN6
Organism   Hydrogenophilus thermoluteolus strain TH-1     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 564902..576221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPTL_RS02750 (HPTL_0530) - 565158..565403 (+) 246 Protein_531 HI0074 family nucleotidyltransferase substrate-binding subunit -
  HPTL_RS02755 (HPTL_0531) - 565400..565762 (+) 363 WP_119334610.1 nucleotidyltransferase family protein -
  HPTL_RS11530 (HPTL_0532) - 565947..566306 (+) 360 WP_119334611.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  HPTL_RS02765 (HPTL_0533) - 566377..568140 (+) 1764 WP_119334612.1 PglL family O-oligosaccharyltransferase -
  HPTL_RS02770 (HPTL_0534) - 568467..569009 (-) 543 WP_119334613.1 Gx transporter family protein -
  HPTL_RS02775 (HPTL_0535) - 569072..569371 (+) 300 WP_119336040.1 nucleotidyltransferase domain-containing protein -
  HPTL_RS02780 (HPTL_0536) - 569368..569925 (+) 558 WP_197713747.1 hypothetical protein -
  HPTL_RS02785 (HPTL_0537) pilR 569902..571221 (-) 1320 WP_119334614.1 sigma-54 dependent transcriptional regulator Regulator
  HPTL_RS02790 (HPTL_0538) - 571313..572206 (+) 894 WP_119334615.1 NAD(P)-dependent oxidoreductase -
  HPTL_RS02795 (HPTL_0539) - 572187..573401 (+) 1215 WP_408610108.1 methionine aminotransferase -
  HPTL_RS02800 (HPTL_0540) - 573401..573682 (+) 282 WP_119334616.1 PP0621 family protein -
  HPTL_RS02805 (HPTL_0541) - 573654..575180 (+) 1527 WP_119334617.1 ATP-binding protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 47466.82 Da        Isoelectric Point: 7.0903

>NTDB_id=70038 HPTL_RS02785 WP_119334614.1 569902..571221(-) (pilR) [Hydrogenophilus thermoluteolus strain TH-1]
MRALIIDDEPDLRLTLKGLLARLGWEAATAATCTEGLERARREPFDLVLTDLRLPDGNGIKLVEALSQEKPELPVAVITA
YGDIDTAVRATKLGAIDFLTKPVARERLAKLLDAVPAPTAPPPSHEADPQTQLIGTSAAITAVRAQITRFAKSLAPVLIQ
GPSGSGKERTARLLHALSPRRHGPFVAVNCGAIPAELIEAELFGVKKGAYTGAHRDRTGLIASAAGGTLFLDEVAELPLP
LQPKLLRVLQERTIRPLGGTEEIPVDVRFVAATHVDLAAAVAEGRFREDLYYRLAVLVVDLPPLTARREDIPLLAEHLIQ
RIAERDQLPPAPITPEALAWLQQQPWPGNVRELENVLARALALSDGAITPQCLTQCTRAHPAAQPQPVEQPPQADEPPLT
PERLRAALAACGGNQSRAAQQLGITLSQLRYRLRKWGIF

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=70038 HPTL_RS02785 WP_119334614.1 569902..571221(-) (pilR) [Hydrogenophilus thermoluteolus strain TH-1]
ATGCGTGCGCTCATCATCGACGACGAACCGGATCTGCGCCTCACCCTGAAGGGGTTGCTCGCCCGCTTGGGGTGGGAGGC
CGCCACCGCCGCCACCTGCACCGAGGGGCTCGAACGCGCGCGCCGTGAACCCTTCGACCTGGTGCTCACCGACCTGCGCC
TGCCCGACGGCAACGGGATCAAGCTTGTCGAAGCACTGAGCCAAGAAAAACCGGAGCTTCCCGTTGCCGTGATCACGGCA
TACGGCGACATCGACACCGCGGTGCGCGCGACCAAGCTCGGCGCGATCGACTTCCTCACCAAACCGGTCGCGCGTGAACG
GTTGGCCAAACTGCTCGACGCAGTACCCGCGCCGACAGCGCCCCCCCCATCGCACGAGGCCGACCCTCAGACGCAACTGA
TCGGCACCAGTGCAGCAATCACCGCAGTGCGTGCACAAATCACCCGTTTCGCGAAGAGCCTGGCGCCGGTCCTCATCCAA
GGGCCTTCGGGTTCCGGCAAAGAGCGCACCGCGCGCCTCCTGCACGCCCTCTCCCCGCGCCGCCACGGGCCGTTCGTTGC
CGTCAACTGTGGCGCGATCCCCGCAGAACTCATCGAAGCGGAACTCTTCGGCGTCAAAAAAGGGGCCTATACCGGCGCCC
ACCGCGACCGCACCGGGCTCATCGCCAGCGCAGCGGGCGGCACCCTCTTCCTGGACGAAGTGGCCGAATTGCCGCTGCCG
CTCCAACCCAAACTCCTGAGGGTGCTCCAAGAGCGCACCATCCGCCCGCTTGGCGGCACCGAAGAGATCCCTGTGGACGT
CCGATTCGTTGCCGCAACGCACGTCGATCTGGCTGCCGCAGTGGCCGAAGGGCGCTTTCGTGAAGACCTCTACTACCGCC
TGGCGGTCCTGGTGGTCGATCTTCCGCCACTGACCGCGCGCCGTGAGGACATTCCGCTCTTGGCCGAACACCTGATCCAG
CGCATCGCGGAACGGGACCAGCTCCCCCCGGCGCCCATCACCCCGGAAGCGCTGGCGTGGCTGCAGCAGCAACCCTGGCC
CGGCAACGTCCGCGAACTGGAAAACGTACTCGCCCGTGCGCTCGCGCTCAGTGACGGCGCGATCACGCCACAGTGCCTCA
CCCAATGCACCCGCGCGCACCCTGCGGCACAGCCCCAACCTGTGGAACAGCCCCCTCAGGCCGACGAGCCACCGCTCACC
CCCGAACGGCTGCGTGCCGCGTTGGCAGCGTGTGGCGGCAACCAATCGCGCGCGGCGCAGCAGTTGGGCATCACGCTGAG
CCAACTGCGCTACCGCTTACGGAAATGGGGTATTTTCTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Sigma-54 interaction domain (Sigma54_activat)

(133-298)

Bacterial regulatory protein, Fis family (HTH_8)

(402-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z6DWN6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

49.21

100

0.497
  pilR Acinetobacter baumannii strain A118

43.413

100

0.458
  luxO Vibrio cholerae strain A1552

38.926

100

0.396

Multiple sequence alignment