Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | NDQ65_RS02345 | Genome accession | NZ_CP098538 |
| Coordinates | 450029..450637 (+) | Length | 202 a.a. |
| NCBI ID | WP_047921003.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain ATCC 49226 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 446078..490387 | 450029..450637 | within | 0 |
Gene organization within MGE regions
Location: 446078..490387
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NDQ65_RS02325 (NDQ65_02320) | dnaB | 446078..447484 (+) | 1407 | WP_003706599.1 | replicative DNA helicase | - |
| NDQ65_RS02330 (NDQ65_02325) | pilH | 447792..448457 (+) | 666 | WP_082298536.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| NDQ65_RS02335 (NDQ65_02330) | pilI | 448489..449106 (+) | 618 | WP_082298535.1 | type IV pilus modification protein PilV | Machinery gene |
| NDQ65_RS02340 (NDQ65_02335) | pilJ | 449103..450050 (+) | 948 | WP_082298534.1 | PilW family protein | Machinery gene |
| NDQ65_RS02345 (NDQ65_02340) | pilK | 450029..450637 (+) | 609 | WP_047921003.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| NDQ65_RS02350 (NDQ65_02345) | pilL | 450639..451112 (+) | 474 | WP_172616930.1 | PilX family type IV pilin | Machinery gene |
| NDQ65_RS02355 (NDQ65_02350) | - | 451182..451490 (-) | 309 | WP_047921007.1 | AzlD family protein | - |
| NDQ65_RS02360 (NDQ65_02355) | - | 451487..452198 (-) | 712 | Protein_460 | AzlC family ABC transporter permease | - |
| NDQ65_RS02365 (NDQ65_02360) | dut | 452364..452816 (+) | 453 | WP_003702446.1 | dUTP diphosphatase | - |
| NDQ65_RS02370 (NDQ65_02365) | dapC | 452894..454081 (+) | 1188 | WP_010359932.1 | succinyldiaminopimelate transaminase | - |
| NDQ65_RS02375 (NDQ65_02370) | yaaA | 454392..455171 (+) | 780 | WP_003706583.1 | peroxide stress protein YaaA | - |
| NDQ65_RS02390 (NDQ65_02385) | - | 455702..456895 (+) | 1194 | WP_010359935.1 | phage integrase central domain-containing protein | - |
| NDQ65_RS02395 (NDQ65_02390) | - | 457251..457520 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| NDQ65_RS02400 (NDQ65_02395) | - | 457715..458398 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| NDQ65_RS11490 | - | 458679..458945 (-) | 267 | Protein_467 | hypothetical protein | - |
| NDQ65_RS02410 (NDQ65_02405) | - | 459056..459271 (-) | 216 | WP_260283716.1 | hypothetical protein | - |
| NDQ65_RS02415 (NDQ65_02410) | - | 459323..459949 (-) | 627 | WP_263584045.1 | siphovirus Gp157 family protein | - |
| NDQ65_RS02420 (NDQ65_02415) | - | 460246..460806 (-) | 561 | WP_260283718.1 | hypothetical protein | - |
| NDQ65_RS02425 (NDQ65_02420) | - | 461128..461298 (-) | 171 | WP_260283719.1 | hypothetical protein | - |
| NDQ65_RS11495 | - | 461451..461781 (-) | 331 | Protein_472 | hypothetical protein | - |
| NDQ65_RS02435 (NDQ65_02430) | - | 461921..462119 (-) | 199 | Protein_473 | hypothetical protein | - |
| NDQ65_RS02440 (NDQ65_02435) | - | 462600..462818 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| NDQ65_RS02445 (NDQ65_02440) | - | 462834..463193 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| NDQ65_RS02450 (NDQ65_02445) | - | 463194..463733 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| NDQ65_RS02455 (NDQ65_02450) | - | 463893..464597 (-) | 705 | WP_003702453.1 | helix-turn-helix transcriptional regulator | - |
| NDQ65_RS02460 (NDQ65_02455) | - | 464725..464940 (+) | 216 | WP_223169978.1 | helix-turn-helix transcriptional regulator | - |
| NDQ65_RS02465 (NDQ65_02460) | - | 465020..465175 (+) | 156 | WP_003691446.1 | hypothetical protein | - |
| NDQ65_RS02470 (NDQ65_02465) | - | 465152..465340 (-) | 189 | WP_003691445.1 | hypothetical protein | - |
| NDQ65_RS02475 (NDQ65_02470) | - | 465513..465740 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| NDQ65_RS02480 (NDQ65_02475) | - | 465858..466856 (+) | 999 | WP_025455934.1 | hypothetical protein | - |
| NDQ65_RS02485 (NDQ65_02480) | - | 466853..468214 (+) | 1362 | WP_047918811.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| NDQ65_RS02490 (NDQ65_02485) | - | 468231..468461 (+) | 231 | WP_033909710.1 | hypothetical protein | - |
| NDQ65_RS02495 (NDQ65_02490) | - | 468552..469046 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| NDQ65_RS02500 (NDQ65_02495) | - | 469223..469372 (+) | 150 | WP_010360014.1 | hypothetical protein | - |
| NDQ65_RS02505 (NDQ65_02500) | - | 469401..469682 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NDQ65_RS02510 (NDQ65_02505) | - | 469673..470047 (+) | 375 | WP_245150965.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NDQ65_RS02515 (NDQ65_02510) | - | 470044..470346 (+) | 303 | WP_003704256.1 | DUF1364 domain-containing protein | - |
| NDQ65_RS02520 (NDQ65_02515) | - | 470343..470726 (+) | 384 | WP_003687982.1 | recombination protein NinB | - |
| NDQ65_RS02525 (NDQ65_02520) | - | 470717..471235 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| NDQ65_RS02530 (NDQ65_02525) | - | 471300..471722 (+) | 423 | WP_003704254.1 | hypothetical protein | - |
| NDQ65_RS02535 (NDQ65_02530) | - | 471722..471964 (+) | 243 | WP_003706439.1 | hypothetical protein | - |
| NDQ65_RS02540 (NDQ65_02535) | - | 472019..472261 (+) | 243 | WP_003687989.1 | hypothetical protein | - |
| NDQ65_RS02545 (NDQ65_02540) | - | 472242..473516 (+) | 1275 | WP_003687990.1 | PBSX family phage terminase large subunit | - |
| NDQ65_RS02550 (NDQ65_02545) | - | 473501..475768 (+) | 2268 | WP_228841300.1 | hypothetical protein | - |
| NDQ65_RS02555 (NDQ65_02550) | - | 476098..476976 (+) | 879 | WP_003706434.1 | KilA-N domain-containing protein | - |
| NDQ65_RS02560 (NDQ65_02555) | - | 477222..478418 (+) | 1197 | WP_003693452.1 | hypothetical protein | - |
| NDQ65_RS02565 (NDQ65_02560) | - | 478415..485743 (+) | 7329 | WP_180374258.1 | PLxRFG domain-containing protein | - |
| NDQ65_RS02570 (NDQ65_02565) | - | 486369..487664 (+) | 1296 | WP_003695011.1 | DUF4043 family protein | - |
| NDQ65_RS02575 (NDQ65_02570) | - | 487719..488192 (+) | 474 | WP_003687996.1 | hypothetical protein | - |
| NDQ65_RS02580 (NDQ65_02575) | - | 488198..488683 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| NDQ65_RS02585 (NDQ65_02580) | - | 488680..488955 (+) | 276 | WP_010358526.1 | hypothetical protein | - |
| NDQ65_RS02590 (NDQ65_02585) | - | 488946..489353 (+) | 408 | WP_010358525.1 | hypothetical protein | - |
| NDQ65_RS02595 (NDQ65_02590) | - | 489344..489505 (+) | 162 | WP_003687999.1 | hypothetical protein | - |
| NDQ65_RS02600 (NDQ65_02595) | - | 489542..490387 (-) | 846 | WP_003701197.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 202 a.a. Molecular weight: 22012.90 Da Isoelectric Point: 7.5809
>NTDB_id=696776 NDQ65_RS02345 WP_047921003.1 450029..450637(+) (pilK) [Neisseria gonorrhoeae strain ATCC 49226]
MRKQNTLTGIPTSDGQRGSALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNGANEETFDNIVVKGKPTVEAVKRSCPAKSGKNSTDLCIDNQGVEYKKGTASVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
MRKQNTLTGIPTSDGQRGSALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNGANEETFDNIVVKGKPTVEAVKRSCPAKSGKNSTDLCIDNQGVEYKKGTASVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
Nucleotide
Download Length: 609 bp
>NTDB_id=696776 NDQ65_RS02345 WP_047921003.1 450029..450637(+) (pilK) [Neisseria gonorrhoeae strain ATCC 49226]
ATGCGCAAACAGAACACTTTGACAGGAATCCCGACTTCTGACGGACAGAGGGGGTCCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACGTTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGGTGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTTCTTGCCCTGCAAAGTCTGGCA
AAAATTCTACCGACCTGTGCATTGACAATCAGGGAGTGGAATATAAGAAAGGGACGGCAAGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
ATGCGCAAACAGAACACTTTGACAGGAATCCCGACTTCTGACGGACAGAGGGGGTCCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACGTTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGGTGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTTCTTGCCCTGCAAAGTCTGGCA
AAAATTCTACCGACCTGTGCATTGACAATCAGGGAGTGGAATATAAGAAAGGGACGGCAAGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
92.611 |
100 |
0.931 |