Detailed information
Bioinformatically predicted
Overview
| Name | comFA/cflA | Type | Machinery gene |
| Locus tag | SR187_RS02035 | Genome accession | NZ_AP018400 |
| Coordinates | 391005..392297 (+) | Length | 430 a.a. |
| NCBI ID | WP_120171355.1 | Uniprot ID | - |
| Organism | Streptococcus ruminantium strain GUT-187 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 393032..402626 | 391005..392297 | flank | 735 |
Gene organization within MGE regions
Location: 391005..402626
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SR187_RS02035 (SR187_2070) | comFA/cflA | 391005..392297 (+) | 1293 | WP_120171355.1 | DEAD/DEAH box helicase | Machinery gene |
| SR187_RS02040 | - | 392290..392955 (+) | 666 | WP_120171356.1 | ComF family protein | - |
| SR187_RS02045 (SR187_2080) | hpf | 393032..393574 (+) | 543 | WP_024533091.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| SR187_RS02115 | - | 401532..402626 (-) | 1095 | Protein_354 | IS3 family transposase | - |
Sequence
Protein
Download Length: 430 a.a. Molecular weight: 49007.55 Da Isoelectric Point: 9.3065
>NTDB_id=69439 SR187_RS02035 WP_120171355.1 391005..392297(+) (comFA/cflA) [Streptococcus ruminantium strain GUT-187]
MNELQDYYGRLFTRNQLTAVERERAQIIPSITEKKTCFRCGTPFEEEYQLPNGAFYCRACLLLGRVRSDEKLYYFPQRDF
PKNTCLQWKGRLTNWQQTISDALCANVEKRQATLVHAVTGAGKTEMIYHTVASVIDSGGAVCLASPRIDVCIELYKRLQQ
DFSVPISLLHGESEAYFRTPMVIATTHQLLKFYRAFDLLLIDEVDAFPYADNPVLYRAVDNAVKPDGVQVFLTATSTDQL
EKKIKAGKLERLSLPRRFHGNPLVVPQKIWFSQFEQYLKKGRLTPKLAKVIQHQRKTGYPLLIFVPEIGKGMEFTKVVKK
AFPNENIGFVSSQTENRLEIVEGFRNKNITILISTTILERGVTFPCVDVFVIQANHYLYSSSSLVQIAGRVGRSQERPTG
LLHFFHEGSTRAIEKSIAEIKQMNKEAGYV
MNELQDYYGRLFTRNQLTAVERERAQIIPSITEKKTCFRCGTPFEEEYQLPNGAFYCRACLLLGRVRSDEKLYYFPQRDF
PKNTCLQWKGRLTNWQQTISDALCANVEKRQATLVHAVTGAGKTEMIYHTVASVIDSGGAVCLASPRIDVCIELYKRLQQ
DFSVPISLLHGESEAYFRTPMVIATTHQLLKFYRAFDLLLIDEVDAFPYADNPVLYRAVDNAVKPDGVQVFLTATSTDQL
EKKIKAGKLERLSLPRRFHGNPLVVPQKIWFSQFEQYLKKGRLTPKLAKVIQHQRKTGYPLLIFVPEIGKGMEFTKVVKK
AFPNENIGFVSSQTENRLEIVEGFRNKNITILISTTILERGVTFPCVDVFVIQANHYLYSSSSLVQIAGRVGRSQERPTG
LLHFFHEGSTRAIEKSIAEIKQMNKEAGYV
Nucleotide
Download Length: 1293 bp
>NTDB_id=69439 SR187_RS02035 WP_120171355.1 391005..392297(+) (comFA/cflA) [Streptococcus ruminantium strain GUT-187]
ATGAATGAATTACAAGATTACTATGGAAGACTATTTACCAGGAATCAACTAACAGCAGTTGAGAGGGAAAGAGCGCAGAT
AATTCCAAGTATTACAGAGAAAAAAACTTGTTTCAGATGCGGAACTCCCTTTGAAGAAGAATACCAGTTGCCAAATGGAG
CTTTTTATTGCCGAGCCTGTTTGCTTTTAGGAAGGGTACGCTCGGACGAAAAACTTTACTATTTTCCACAGAGAGACTTT
CCTAAAAATACCTGCTTACAGTGGAAAGGACGACTGACCAATTGGCAACAAACCATTTCTGATGCTCTTTGCGCCAATGT
TGAGAAAAGGCAAGCTACGCTGGTTCATGCAGTAACAGGAGCTGGAAAAACAGAGATGATATATCATACAGTAGCTTCTG
TTATTGATAGTGGTGGAGCAGTTTGTTTAGCTAGTCCACGAATTGATGTTTGTATCGAACTCTATAAACGCTTGCAGCAG
GATTTTTCAGTTCCAATTAGTCTCTTGCACGGAGAATCAGAGGCCTACTTTAGAACCCCCATGGTTATTGCTACAACTCA
TCAGCTCTTAAAATTTTATCGTGCTTTTGATTTGCTTTTGATTGATGAAGTAGATGCCTTTCCATACGCAGATAATCCTG
TTCTTTATCGGGCAGTAGACAATGCAGTAAAACCAGATGGTGTACAGGTATTTTTGACAGCTACTTCAACAGATCAACTT
GAGAAAAAGATAAAAGCAGGAAAACTAGAACGCCTTAGTTTGCCCAGACGATTTCATGGCAATCCACTAGTAGTACCACA
AAAAATTTGGTTCAGCCAATTTGAACAGTATCTAAAGAAAGGTAGATTGACCCCTAAGCTGGCAAAGGTTATCCAGCATC
AGCGAAAGACAGGCTATCCCTTGCTAATATTTGTTCCAGAAATCGGAAAAGGGATGGAATTTACAAAGGTAGTCAAAAAA
GCATTTCCTAATGAAAACATTGGTTTTGTTTCCAGTCAGACAGAAAATCGCCTGGAGATAGTAGAAGGATTTCGCAATAA
AAACATCACCATTTTAATCTCAACCACCATTCTTGAACGCGGTGTAACCTTCCCTTGTGTTGATGTCTTTGTTATTCAGG
CCAATCATTATCTCTATAGTTCATCTAGTTTAGTTCAAATAGCAGGTCGAGTTGGTCGCAGCCAAGAACGACCAACAGGG
CTTCTACATTTTTTTCACGAAGGAAGCACGCGGGCGATTGAAAAGTCCATCGCTGAAATCAAACAAATGAATAAGGAGGC
AGGTTATGTCTAA
ATGAATGAATTACAAGATTACTATGGAAGACTATTTACCAGGAATCAACTAACAGCAGTTGAGAGGGAAAGAGCGCAGAT
AATTCCAAGTATTACAGAGAAAAAAACTTGTTTCAGATGCGGAACTCCCTTTGAAGAAGAATACCAGTTGCCAAATGGAG
CTTTTTATTGCCGAGCCTGTTTGCTTTTAGGAAGGGTACGCTCGGACGAAAAACTTTACTATTTTCCACAGAGAGACTTT
CCTAAAAATACCTGCTTACAGTGGAAAGGACGACTGACCAATTGGCAACAAACCATTTCTGATGCTCTTTGCGCCAATGT
TGAGAAAAGGCAAGCTACGCTGGTTCATGCAGTAACAGGAGCTGGAAAAACAGAGATGATATATCATACAGTAGCTTCTG
TTATTGATAGTGGTGGAGCAGTTTGTTTAGCTAGTCCACGAATTGATGTTTGTATCGAACTCTATAAACGCTTGCAGCAG
GATTTTTCAGTTCCAATTAGTCTCTTGCACGGAGAATCAGAGGCCTACTTTAGAACCCCCATGGTTATTGCTACAACTCA
TCAGCTCTTAAAATTTTATCGTGCTTTTGATTTGCTTTTGATTGATGAAGTAGATGCCTTTCCATACGCAGATAATCCTG
TTCTTTATCGGGCAGTAGACAATGCAGTAAAACCAGATGGTGTACAGGTATTTTTGACAGCTACTTCAACAGATCAACTT
GAGAAAAAGATAAAAGCAGGAAAACTAGAACGCCTTAGTTTGCCCAGACGATTTCATGGCAATCCACTAGTAGTACCACA
AAAAATTTGGTTCAGCCAATTTGAACAGTATCTAAAGAAAGGTAGATTGACCCCTAAGCTGGCAAAGGTTATCCAGCATC
AGCGAAAGACAGGCTATCCCTTGCTAATATTTGTTCCAGAAATCGGAAAAGGGATGGAATTTACAAAGGTAGTCAAAAAA
GCATTTCCTAATGAAAACATTGGTTTTGTTTCCAGTCAGACAGAAAATCGCCTGGAGATAGTAGAAGGATTTCGCAATAA
AAACATCACCATTTTAATCTCAACCACCATTCTTGAACGCGGTGTAACCTTCCCTTGTGTTGATGTCTTTGTTATTCAGG
CCAATCATTATCTCTATAGTTCATCTAGTTTAGTTCAAATAGCAGGTCGAGTTGGTCGCAGCCAAGAACGACCAACAGGG
CTTCTACATTTTTTTCACGAAGGAAGCACGCGGGCGATTGAAAAGTCCATCGCTGAAATCAAACAAATGAATAAGGAGGC
AGGTTATGTCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comFA/cflA | Streptococcus pneumoniae Rx1 |
64.554 |
99.07 |
0.64 |
| comFA/cflA | Streptococcus pneumoniae D39 |
64.554 |
99.07 |
0.64 |
| comFA/cflA | Streptococcus pneumoniae R6 |
64.554 |
99.07 |
0.64 |
| comFA/cflA | Streptococcus pneumoniae TIGR4 |
64.554 |
99.07 |
0.64 |
| comFA/cflA | Streptococcus mitis NCTC 12261 |
63.85 |
99.07 |
0.633 |
| comFA/cflA | Streptococcus mitis SK321 |
63.146 |
99.07 |
0.626 |
| comFA | Lactococcus lactis subsp. cremoris KW2 |
53.652 |
92.326 |
0.495 |
| comFA | Latilactobacillus sakei subsp. sakei 23K |
38.462 |
99.767 |
0.384 |