Detailed information NTG0692960

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: M9H69_RS09860
• Genome accession: NZ_CP097843
• Coordinates: 1963139..1964437 (-)
• Length: 432 a.a.
• NCBI ID: WP_250315525.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain HP01
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1958139..1969437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS09835 (M9H69_09835)	-	1958270..1959448 (-)	1179	WP_250315523.1	acetyl-CoA C-acetyltransferase	-
M9H69_RS09840 (M9H69_09840)	-	1959467..1960315 (-)	849	WP_025172369.1	3-hydroxybutyryl-CoA dehydrogenase	-
M9H69_RS09845 (M9H69_09845)	-	1960396..1961604 (-)	1209	WP_000201481.1	acyl-CoA dehydrogenase family protein	-
M9H69_RS09850 (M9H69_09850)	raiA	1961852..1962400 (-)	549	WP_000599116.1	ribosome-associated translation inhibitor RaiA	-
M9H69_RS09855 (M9H69_09855)	comFC/cflB	1962480..1963142 (-)	663	WP_250315524.1	ComF family protein	Machinery gene
M9H69_RS09860 (M9H69_09860)	comFA/cflA	1963139..1964437 (-)	1299	WP_250315525.1	DEAD/DEAH box helicase	Machinery gene
M9H69_RS09865 (M9H69_09865)	-	1964494..1965129 (+)	636	WP_250315526.1	YigZ family protein	-
M9H69_RS09870 (M9H69_09870)	-	1965145..1965588 (+)	444	WP_250315527.1	PH domain-containing protein	-
M9H69_RS09875 (M9H69_09875)	cysK	1965685..1966611 (+)	927	WP_000158480.1	cysteine synthase A	-
M9H69_RS09880 (M9H69_09880)	-	1966827..1967355 (+)	529	Protein_1908	transposase	-
M9H69_RS09885 (M9H69_09885)	-	1967726..1967938 (-)	213	WP_350027869.1	helix-turn-helix domain-containing protein	-
M9H69_RS09890 (M9H69_09890)	-	1968091..1969042 (+)	952	Protein_1910	transposase	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 49588.64 Da
• Isoelectric Point: 8.5231

>NTDB_id=692960 M9H69_RS09860 WP_250315525.1 1963139..1964437(-) (comFA/cflA) [Streptococcus oralis strain HP01]
MKVNPNYLGRLFTEKELTEEERQMAVKLPAMRKEKGKLLCQRCNSTILEEWYLPIGAYYCRECLLMKRVRSDQALYHFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLIRAVKKKEPTLVHAVTGAGKTEMIYQVVAKVIDEGGAVCLASPRIDVCLELYKR
LQNDFACEIALLHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYIDNTILYYAVKNSVKEDGLRIFLTATST
DELDRKVRTGELKQLSLPRRFHGNPLIVPKPVWLSDFNRCLEKSQLSSKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LQVHFPDENIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHQLITKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNTSIKKAIKEIKQMNKEARL

Nucleotide

• Length: 1299 bp

>NTDB_id=692960 M9H69_RS09860 WP_250315525.1 1963139..1964437(-) (comFA/cflA) [Streptococcus oralis strain HP01]
ATGAAAGTAAATCCAAATTACCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTGAAGAGGAACGACAGATGGCGGTGAA
ACTGCCGGCAATGAGAAAAGAGAAGGGAAAATTGCTTTGTCAACGTTGTAATAGTACGATTCTAGAGGAATGGTATTTGC
CTATCGGTGCCTACTATTGCAGGGAGTGTTTACTGATGAAGCGAGTCAGGAGTGATCAAGCATTATACCATTTTCCGCAG
GAAGATTTTCCTAAGCAAGATGTTCTCAAATGGCGTGGTCAGTTAACCCCTTTTCAGGAAAAGGTGTCAGAGGGATTGAT
CCGAGCAGTTAAAAAGAAGGAACCGACTTTAGTTCATGCTGTAACAGGAGCTGGAAAGACGGAGATGATTTATCAGGTTG
TGGCCAAAGTGATTGATGAAGGTGGTGCAGTTTGTTTGGCCAGCCCTCGAATCGATGTGTGTTTGGAGCTGTATAAACGA
CTACAGAATGACTTTGCTTGTGAGATAGCACTACTTCATGGTGAGTCAGAACCCTATTTTCGAACACCACTAGTTGTTGC
AACGACTCATCAGCTGTTAAAATTTTATCATGCTTTTGACTTGCTGATAGTGGATGAGGTAGATGCCTTTCCCTATATTG
ACAATACTATACTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTAAGGATATTCCTTACAGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCGCACAGGAGAATTAAAACAATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TGTTCCCAAACCTGTCTGGTTATCAGATTTTAATCGCTGTTTAGAGAAAAGTCAGTTGTCATCCAAGTTAAAGACCTACA
TTGAGAAACAGAGAAGAACAGGTTACCCCTTACTGATTTTTGCATCAGAGATTAAGAAAGGCGAAAAACTAAAAGAAATA
CTACAGGTGCATTTCCCAGATGAGAATATCGGTTTTGTATCTTCTGTCACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTGACAATACTGATTAGTACAACAATATTGGAACGCGGGGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCAACTCATTACCAAGTCTAGTTTAATTCAGATTGGTGGTCGAGTTGGGCGTAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATACTTCCATCAAGAAGGCAATCAAGGAAATCAAGCAGATGAA
CAAGGAGGCGAGATTATGA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (291-396)

• Type III restriction enzyme, res subunit (ResIII) (94-168)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus mitis NCTC 12261	89.583	100	0.896
comFA/cflA	Streptococcus mitis SK321	89.12	100	0.891
comFA/cflA	Streptococcus pneumoniae Rx1	87.963	100	0.88
comFA/cflA	Streptococcus pneumoniae D39	87.963	100	0.88
comFA/cflA	Streptococcus pneumoniae R6	87.963	100	0.88
comFA/cflA	Streptococcus pneumoniae TIGR4	87.731	100	0.877
comFA	Lactococcus lactis subsp. cremoris KW2	50.864	93.75	0.477
comFA	Latilactobacillus sakei subsp. sakei 23K	38.128	100	0.387