Detailed information NTG0692907

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: M9H69_RS01490
• Genome accession: NZ_CP097843
• Coordinates: 266230..267240 (+)
• Length: 336 a.a.
• NCBI ID: WP_007519606.1
• Uniprot ID: X8K729
• Organism: Streptococcus oralis strain HP01
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 261230..272240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS01465 (M9H69_01465)	-	261662..262984 (+)	1323	WP_250315718.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
M9H69_RS01470 (M9H69_01470)	folE	262965..263519 (+)	555	WP_000380933.1	GTP cyclohydrolase I FolE	-
M9H69_RS01475 (M9H69_01475)	folK	263561..264382 (+)	822	WP_250315719.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
M9H69_RS01480 (M9H69_01480)	-	264375..265658 (+)	1284	WP_250315720.1	DUF308 domain-containing protein	-
M9H69_RS01485 (M9H69_01485)	-	265709..266026 (-)	318	WP_000886045.1	DUF960 domain-containing protein	-
M9H69_RS01490 (M9H69_01490)	ccpA	266230..267240 (+)	1011	WP_007519606.1	catabolite control protein A	Regulator
M9H69_RS01495 (M9H69_01495)	-	267294..268256 (-)	963	WP_250315721.1	asparaginase	-
M9H69_RS01500 (M9H69_01500)	-	268322..269716 (+)	1395	WP_250315722.1	Cof-type HAD-IIB family hydrolase	-
M9H69_RS01505 (M9H69_01505)	-	269750..270202 (-)	453	WP_000079165.1	universal stress protein	-
M9H69_RS01510 (M9H69_01510)	-	270449..271663 (+)	1215	WP_195217332.1	pyridoxal phosphate-dependent aminotransferase	-
M9H69_RS01515 (M9H69_01515)	rpmH	271808..271942 (+)	135	WP_000831902.1	50S ribosomal protein L34	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37242.29 Da
• Isoelectric Point: 5.5033

>NTDB_id=692907 M9H69_RS01490 WP_007519606.1 266230..267240(+) (ccpA) [Streptococcus oralis strain HP01]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYVLAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=692907 M9H69_RS01490 WP_007519606.1 266230..267240(+) (ccpA) [Streptococcus oralis strain HP01]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACGGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCCCGTGGTTTAGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCGAACATTACCAATGGTTATTTCTCA
ACGCTTGCTAAGGGAATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTCGAACACCAACTTCCAAGT
GTGAATATCGACTACAAACAAGCAACGATTGATGCTGTGAGCTATCTTCTCAAAGAAAATGAGAAAATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATCGGTTACAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGCGAGGGTTTGGTCTTTGAATCAAAATACAGCTATGACGATGGCTATGTCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCAGCGGGTGTGTTGAATGGTTTGGCTGACCATGGTGTATCTGTGCC
AGAAGAGTTTGAAATCATCACGACAGATGACTCTCAAATTGCACGATTCACTCGTCCAAACTTGACGACTATTGCCCAAC
CTCTTTATGACTTAGGTGCTATCAGTATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCCTACCTCATGGTTTGACAGAACGTCGTTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: X8K729

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.048	100	0.94
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.402	98.512	0.565