Detailed information NTG0690839

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M8969_RS05300
• Genome accession: NZ_CP097593
• Coordinates: 1056667..1057830 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UA0229
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1051667..1062830

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8969_RS05280	-	1052107..1053303 (+)	1197	WP_032876154.1	glycosyltransferase	-
M8969_RS05285	-	1053436..1054512 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
M8969_RS05290	-	1054611..1055792 (-)	1182	WP_032876157.1	LCP family protein	-
M8969_RS05295	-	1055797..1056444 (-)	648	WP_007614107.1	YigZ family protein	-
M8969_RS05300	degS	1056667..1057830 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
M8969_RS05305	degU	1057907..1058596 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M8969_RS05310	-	1058694..1059542 (+)	849	WP_032876160.1	DegV family protein	-
M8969_RS05315	comFA	1059651..1061036 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
M8969_RS05320	-	1061094..1061378 (+)	285	WP_003151389.1	competence protein ComFB	-
M8969_RS05325	comFC	1061384..1062073 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
M8969_RS05330	-	1062147..1062566 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=690839 M8969_RS05300 WP_007407484.1 1056667..1057830(+) (degS) [Bacillus velezensis strain UA0229]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=690839 M8969_RS05300 WP_007407484.1 1056667..1057830(+) (degS) [Bacillus velezensis strain UA0229]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951