Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M8966_RS14135 Genome accession   NZ_CP097589
Coordinates   2890744..2891400 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain UA0311     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2885744..2896400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8966_RS14115 spxH 2885983..2886885 (+) 903 WP_012117287.1 protease adaptor protein SpxH -
  M8966_RS14120 - 2887171..2887338 (+) 168 WP_003155026.1 hypothetical protein -
  M8966_RS14125 pepF 2887376..2889205 (-) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  M8966_RS14130 - 2889433..2890593 (-) 1161 WP_012117286.1 competence protein CoiA family protein -
  M8966_RS14135 mecA 2890744..2891400 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  M8966_RS14145 - 2891676..2892332 (+) 657 WP_012117285.1 TerC family protein -
  M8966_RS14150 spx 2892390..2892785 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  M8966_RS14155 - 2892964..2893542 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  M8966_RS14160 - 2893651..2894847 (-) 1197 WP_012117284.1 putative glycoside hydrolase -
  M8966_RS14165 oppF 2894954..2895871 (-) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=690649 M8966_RS14135 WP_003155032.1 2890744..2891400(-) (mecA) [Bacillus velezensis strain UA0311]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=690649 M8966_RS14135 WP_003155032.1 2890744..2891400(-) (mecA) [Bacillus velezensis strain UA0311]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
GGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895