Detailed information NTG0690607

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M8966_RS02315
• Genome accession: NZ_CP097589
• Coordinates: 452960..454123 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UA0311
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 447960..459123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8966_RS02285	-	448225..448644 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
M8966_RS02290	comFC	448718..449407 (-)	690	WP_197197403.1	double zinc ribbon domain-containing protein	Machinery gene
M8966_RS02295	-	449413..449697 (-)	285	WP_007407481.1	competence protein ComFB	-
M8966_RS02300	comFA	449755..451140 (-)	1386	WP_012118573.1	DEAD/DEAH box helicase	Machinery gene
M8966_RS02305	-	451248..452096 (-)	849	WP_003151387.1	DegV family protein	-
M8966_RS02310	degU	452194..452883 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M8966_RS02315	degS	452960..454123 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
M8966_RS02320	-	454346..454993 (+)	648	WP_007614107.1	YigZ family protein	-
M8966_RS02325	-	454998..456218 (+)	1221	WP_012118574.1	LCP family protein	-
M8966_RS02330	-	456317..457393 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
M8966_RS02335	-	457526..458722 (-)	1197	WP_012118575.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=690607 M8966_RS02315 WP_007407484.1 452960..454123(-) (degS) [Bacillus velezensis strain UA0311]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=690607 M8966_RS02315 WP_007407484.1 452960..454123(-) (degS) [Bacillus velezensis strain UA0311]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951