Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   OTB22_RS01655 Genome accession   NZ_CP113267
Coordinates   314140..316245 (+) Length   701 a.a.
NCBI ID   WP_268217997.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 309140..321245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS01640 (OTB22_01645) mraY 310844..311824 (+) 981 WP_268217995.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  OTB22_RS01645 (OTB22_01650) - 312192..313538 (+) 1347 WP_268217916.1 IS1380-like element ISSpn5 family transposase -
  OTB22_RS01650 (OTB22_01655) - 313720..313884 (+) 165 WP_268217996.1 hypothetical protein -
  OTB22_RS01655 (OTB22_01660) clpC 314140..316245 (+) 2106 WP_268217997.1 AAA family ATPase Regulator
  OTB22_RS01660 (OTB22_01665) - 316440..317786 (-) 1347 WP_268217916.1 IS1380-like element ISSpn5 family transposase -
  OTB22_RS01665 (OTB22_01670) treR 318021..318731 (-) 711 WP_000760673.1 trehalose operon repressor Regulator
  OTB22_RS01670 (OTB22_01675) treP 318916..320883 (+) 1968 WP_268217998.1 PTS system trehalose-specific EIIBC component -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77679.44 Da        Isoelectric Point: 4.7080

>NTDB_id=690607 OTB22_RS01655 WP_268217997.1 314140..316245(+) (clpC) [Streptococcus pneumoniae strain BC2]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEVNLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=690607 OTB22_RS01655 WP_268217997.1 314140..316245(+) (clpC) [Streptococcus pneumoniae strain BC2]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTACGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGATGGTGTCCTTGCAAAACTAGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGAATACTTTTAAAATTCT
TCAAGGCATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAGGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGTTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGTCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTTAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGAGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTAGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(259-354)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.436

100

0.475
  clpE Streptococcus mutans UA159

48.91

91.583

0.448
  clpE Streptococcus pneumoniae Rx1

47.31

90.157

0.427
  clpE Streptococcus pneumoniae D39

47.31

90.157

0.427
  clpE Streptococcus pneumoniae R6

47.31

90.157

0.427
  clpE Streptococcus pneumoniae TIGR4

47.235

90.3

0.427
  clpC Bacillus subtilis subsp. subtilis str. 168

44.838

92.582

0.415
  clpC Streptococcus pneumoniae Rx1

41.911

92.582

0.388
  clpC Streptococcus pneumoniae D39

41.911

92.582

0.388
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.846

92.725

0.388
  clpC Streptococcus pneumoniae TIGR4

41.757

92.582

0.387
  clpC Streptococcus thermophilus LMD-9

42.338

90.3

0.382
  clpC Streptococcus thermophilus LMG 18311

42.18

90.3

0.381
  clpC Streptococcus mutans UA159

41.909

88.16

0.369