Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   OS912_RS01265 Genome accession   NZ_CP113266
Coordinates   254334..254798 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain BC1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 249334..259798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS01245 (OS912_01250) - 250285..251253 (-) 969 WP_000105362.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  OS912_RS01250 (OS912_01255) pdrM 251407..252768 (-) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  OS912_RS01255 (OS912_01260) - 252779..253039 (-) 261 WP_001105925.1 hypothetical protein -
  OS912_RS01260 (OS912_01265) - 253053..254321 (-) 1269 WP_000924481.1 dihydroorotase -
  OS912_RS01265 (OS912_01270) mutX 254334..254798 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  OS912_RS01270 (OS912_01275) - 254808..255461 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  OS912_RS01275 (OS912_01280) - 255597..256199 (-) 603 WP_014931947.1 hypothetical protein -
  OS912_RS01280 (OS912_01285) - 256257..256970 (-) 714 WP_061752147.1 YjjG family noncanonical pyrimidine nucleotidase -
  OS912_RS01285 (OS912_01290) dhaM 257429..257788 (-) 360 WP_000443790.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  OS912_RS11030 - 257788..257862 (-) 75 Protein_260 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=690486 OS912_RS01265 WP_001135768.1 254334..254798(-) (mutX) [Streptococcus pneumoniae strain BC1]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=690486 OS912_RS01265 WP_001135768.1 254334..254798(-) (mutX) [Streptococcus pneumoniae strain BC1]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987