Detailed information NTG0069009

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPYKS030_RS07985
• Genome accession: NZ_AP018337
• Coordinates: 1500950..1501951 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain KS030
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1495950..1506951

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYKS030_RS07970 (SPYKS030_15100)	thrS	1496120..1498063 (-)	1944	WP_011054265.1	threonine--tRNA ligase	-
SPYKS030_RS07975 (SPYKS030_15110)	-	1498485..1499819 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
SPYKS030_RS07980 (SPYKS030_15120)	-	1499821..1500819 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
SPYKS030_RS07985 (SPYKS030_15130)	ccpA	1500950..1501951 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
SPYKS030_RS07990 (SPYKS030_15140)	-	1502125..1503210 (+)	1086	WP_011054264.1	aminopeptidase P family protein	-
SPYKS030_RS07995 (SPYKS030_15150)	-	1503259..1503924 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
SPYKS030_RS08000 (SPYKS030_15160)	-	1503935..1504312 (+)	378	WP_002985686.1	VOC family protein	-
SPYKS030_RS08005 (SPYKS030_15170)	-	1504457..1505383 (+)	927	WP_011106859.1	glycosyltransferase family 2 protein	-
SPYKS030_RS08010 (SPYKS030_15180)	-	1505594..1506277 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=69009 SPYKS030_RS07985 WP_002985680.1 1500950..1501951(-) (ccpA) [Streptococcus pyogenes strain KS030]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=69009 SPYKS030_RS07985 WP_002985680.1 1500950..1501951(-) (ccpA) [Streptococcus pyogenes strain KS030]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559