Detailed information NTG0068988

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: HT085_RS08920
• Genome accession: NZ_AP023069
• Coordinates: 1703570..1704154 (+)
• Length: 194 a.a.
• NCBI ID: WP_003689924.1
• Uniprot ID: Q5F636
• Organism: Neisseria gonorrhoeae strain TUM19854
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1698570..1709154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HT085_RS08885	-	1699312..1699419 (+)	108	Protein_1721	IS5/IS1182 family transposase	-
HT085_RS08890 (TUM19854C_17000)	-	1699500..1700288 (-)	789	WP_003689910.1	hypothetical protein	-
HT085_RS08895 (TUM19854C_17010)	bioH	1700285..1701034 (-)	750	WP_010360850.1	pimeloyl-ACP methyl ester esterase BioH	-
HT085_RS08900 (TUM19854C_17020)	-	1701033..1701758 (+)	726	WP_003689912.1	ComF family protein	-
HT085_RS08905 (TUM19854C_17030)	trmL	1701823..1702287 (+)	465	WP_003689916.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
HT085_RS08910 (TUM19854C_17040)	-	1702415..1703101 (+)	687	WP_003689919.1	septal ring lytic transglycosylase RlpA family protein	-
HT085_RS08915 (TUM19854C_17050)	-	1703162..1703488 (+)	327	WP_003689921.1	PepSY domain-containing protein	-
HT085_RS08920 (TUM19854C_17060)	ruvA	1703570..1704154 (+)	585	WP_003689924.1	Holliday junction branch migration protein RuvA	Machinery gene
HT085_RS08925	-	1704154..1704291 (+)	138	WP_003689926.1	hypothetical protein	-
HT085_RS08930 (TUM19854C_17070)	-	1704317..1706173 (+)	1857	WP_003689927.1	ABC transporter ATP-binding protein	-
HT085_RS08935 (TUM19854C_17080)	rsgA	1706178..1707101 (+)	924	WP_003689928.1	ribosome small subunit-dependent GTPase A	-
HT085_RS08945 (TUM19854C_17090)	-	1707127..1707438 (+)	312	WP_003697631.1	exodeoxyribonuclease VII small subunit	-
HT085_RS08950 (TUM19854C_17100)	-	1707422..1708318 (+)	897	WP_003691917.1	polyprenyl synthetase family protein	-
HT085_RS08955 (TUM19854C_17120)	-	1708435..1708734 (-)	300	WP_010359269.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20729.99 Da
• Isoelectric Point: 6.4967

>NTDB_id=68988 HT085_RS08920 WP_003689924.1 1703570..1704154(+) (ruvA) [Neisseria gonorrhoeae strain TUM19854]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAASPAADETEDIVSTLLA
LGYNEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=68988 HT085_RS08920 WP_003689924.1 1703570..1704154(+) (ruvA) [Neisseria gonorrhoeae strain TUM19854]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGTTATGA
AGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCTCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCTCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAACGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCCCTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q5F636

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	34.951	100	0.371