Detailed information NTG0689659

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M8X21_RS18305
• Genome accession: NZ_CP097467
• Coordinates: 3658192..3659355 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain HMB26553
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3653192..3664355

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8X21_RS18275 (M8X21_18275)	-	3653457..3653876 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
M8X21_RS18280 (M8X21_18280)	comFC	3653950..3654639 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
M8X21_RS18285 (M8X21_18285)	-	3654645..3654929 (-)	285	WP_003151389.1	competence protein ComFB	-
M8X21_RS18290 (M8X21_18290)	comFA	3654987..3656372 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
M8X21_RS18295 (M8X21_18295)	-	3656480..3657328 (-)	849	WP_003151387.1	DegV family protein	-
M8X21_RS18300 (M8X21_18300)	degU	3657426..3658115 (-)	690	WP_103042074.1	two-component system response regulator DegU	Regulator
M8X21_RS18305 (M8X21_18305)	degS	3658192..3659355 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
M8X21_RS18310 (M8X21_18310)	-	3659578..3660225 (+)	648	WP_007614107.1	YigZ family protein	-
M8X21_RS18315 (M8X21_18315)	-	3660230..3661444 (+)	1215	WP_014419013.1	LCP family protein	-
M8X21_RS18320 (M8X21_18320)	-	3661543..3662619 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
M8X21_RS18325 (M8X21_18325)	-	3662752..3663948 (-)	1197	WP_029972825.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=689659 M8X21_RS18305 WP_007407484.1 3658192..3659355(-) (degS) [Bacillus velezensis strain HMB26553]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=689659 M8X21_RS18305 WP_007407484.1 3658192..3659355(-) (degS) [Bacillus velezensis strain HMB26553]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951