Detailed information NTG0687461

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M2M89_RS17955
• Genome accession: NZ_CP097130
• Coordinates: 3493934..3495091 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain S16
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3488934..3500091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M2M89_RS17925	yvyF	3489187..3489606 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
M2M89_RS17930	comFC	3489680..3490402 (-)	723	WP_014481051.1	comF operon protein ComFC	Machinery gene
M2M89_RS17935	comFB	3490366..3490662 (-)	297	WP_003227989.1	late competence protein ComFB	-
M2M89_RS17940	comFA	3490722..3492113 (-)	1392	WP_041850475.1	ATP-dependent helicase ComFA	Machinery gene
M2M89_RS17945	fakBA	3492219..3493064 (-)	846	WP_003227986.1	DegV family protein	-
M2M89_RS17950	degU	3493162..3493851 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M2M89_RS17955	degS	3493934..3495091 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
M2M89_RS17960	yvyE	3495308..3495961 (+)	654	WP_003227979.1	YigZ family protein	-
M2M89_RS17965	tagV	3495961..3497136 (+)	1176	WP_128441886.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
M2M89_RS17970	tagO	3497209..3498285 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
M2M89_RS17975	tuaH	3498430..3499623 (-)	1194	WP_080332566.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=687461 M2M89_RS17955 WP_003227983.1 3493934..3495091(-) (degS) [Bacillus subtilis strain S16]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=687461 M2M89_RS17955 WP_003227983.1 3493934..3495091(-) (degS) [Bacillus subtilis strain S16]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGTGAGCAGTCACGCCAGCAGTATGAACAGCTGGTTGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCAGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1