Detailed information NTG0068699

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: KK0981_RS09515
• Genome accession: NZ_AP017971
• Coordinates: 1779131..1780198 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159562.1
• Uniprot ID: B1I897
• Organism: Streptococcus pneumoniae strain KK0981
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1774131..1785198

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KK0981_RS09500 (KK0981_38520)	treR	1775928..1776638 (+)	711	WP_050201350.1	trehalose operon repressor	Regulator
KK0981_RS09505	-	1776793..1778119 (+)	1327	Protein_1797	transposase	-
KK0981_RS09510 (KK0981_38560)	amiF	1778194..1779120 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
KK0981_RS09515 (KK0981_38570)	amiE	1779131..1780198 (-)	1068	WP_000159562.1	ABC transporter ATP-binding protein	Regulator
KK0981_RS09520 (KK0981_38580)	amiD	1780207..1781133 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
KK0981_RS09525 (KK0981_38590)	amiC	1781133..1782629 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
KK0981_RS09530 (KK0981_38600)	amiA3	1782696..1784675 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=68699 KK0981_RS09515 WP_000159562.1 1779131..1780198(-) (amiE) [Streptococcus pneumoniae strain KK0981]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKEWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=68699 KK0981_RS09515 WP_000159562.1 1779131..1780198(-) (amiE) [Streptococcus pneumoniae strain KK0981]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGAGTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: B1I897

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538