Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   IGS56_RS06140 Genome accession   NZ_AP022846
Coordinates   1252369..1254408 (-) Length   679 a.a.
NCBI ID   WP_071163269.1    Uniprot ID   -
Organism   Haemophilus influenzae strain TAMBA230     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1247369..1259408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS56_RS06130 (JPHIA_11560) - 1247919..1250189 (+) 2271 WP_005650195.1 NADP-dependent malic enzyme -
  IGS56_RS06135 (JPHIA_11570) - 1250413..1252338 (+) 1926 WP_071163268.1 LTA synthase family protein -
  IGS56_RS06140 (JPHIA_11580) uvrB 1252369..1254408 (-) 2040 WP_071163269.1 excinuclease ABC subunit UvrB Machinery gene
  IGS56_RS06150 (JPHIA_11590) zevB 1255023..1255991 (-) 969 WP_071163270.1 zinc transporter permease subunit ZevB -
  IGS56_RS06155 (JPHIA_11600) zevA 1255994..1256614 (-) 621 WP_005650213.1 zinc transporter binding subunit ZevA -
  IGS56_RS06160 (JPHIA_11610) - 1256965..1257240 (+) 276 WP_071163271.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  IGS56_RS06165 (JPHIA_11620) - 1257237..1257500 (+) 264 WP_071163272.1 type II toxin-antitoxin system YafQ family toxin -
  IGS56_RS06170 (JPHIA_11630) ettA 1257584..1259254 (+) 1671 WP_005650218.1 energy-dependent translational throttle protein EttA -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 77512.98 Da        Isoelectric Point: 5.0392

>NTDB_id=68697 IGS56_RS06140 WP_071163269.1 1252369..1254408(-) (uvrB) [Haemophilus influenzae strain TAMBA230]
MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYA
EMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYL
QMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFHVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSF
GAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSG
RNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSAT
PGPYELEKSGCEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRY
LHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYAD
SITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEATALYNAPKNAKEYQQ
QIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=68697 IGS56_RS06140 WP_071163269.1 1252369..1254408(-) (uvrB) [Haemophilus influenzae strain TAMBA230]
ATGTCTGAAAAAATCAACACAAAACCATTCATTCTGCATTCCGACTTTCGTCCCTCTGGCGATCAGCCACAAGCTATCGA
AAAATTGGCTGAAAATTTAACGGATGGTTTGGCGCATCAAACTTTACTCGGGGTAACTGGCTCGGGGAAGACGTTTACTA
TCGCCAATGTAATCGCTCAATTAAATCGCCCCGCGATGTTACTTGCACCGAATAAAACCCTTGCTGCTCAGCTTTATGCA
GAAATGAAAGCTTTTTTTCCAGAAAATGCGGTGGAATATTTTGTGTCTTACTATGATTATTATCAGCCAGAAGCCTATGT
GCCGAGCAGTGATACATTTATTGAAAAAGATGCGTCTATTAATGATCAAATTGAACAAATGCGACTTTCTGCGACGAAAT
CTTTTCTAGAACGTCGAGATACCATCGTGGTGGCTTCTGTTTCTGCAATTTATGGTTTGGGCGATCCTGATAGCTATTTA
CAAATGATGTTGCATTTACAACAAGGTGCCATTATCGATCAACGCCAAATTTTAGCGAAATTAGCGGAATTACAATATAC
CCGAAATGATCAAGCATTTCAGCGTGGAACTTTCCATGTTCGCGGAGAAATTATTGATATTTTCCCTGCGGAATCTGATG
ATCGTGCGGTGCGTATTGAATTATTTGATGATGAAATCGAGCGTTTAAGTTTATTTGATCCGCTCACTGGTAGTAGTTTT
GGTGCTGTACCACGTTTTACGATCTATCCTAAAACTCACTATGTGACACCAAGAGAACGTATTTTAGATGCGATAGAAAA
CATCAAAAAAGAACTGGTATCACGCCGTGAATACTTCATTAAAGAACATAAACTTTTAGAAGAACAGCGTATCAGCCAAC
GAACCCAATTTGATATTGAAATGATGAATGAATTGGGCTATTGCTCGGGAATTGAAAACTACTCTCGCTATTTATCGGGC
AGAAATGAGGGCGAACCACCACCAACATTATTTGATTATATGCCCTCTGATGCGATTTTAATTATTGATGAATCTCATGT
AACTGTGCCTCAAATTGGCGGGATGTATCGTGGCGACCGTTCACGTAAAGAAACCTTAGTCGAATATGGTTTCCGTTTGC
CGTCCGCATTGGATAATCGTCCGTTACGCTTTGAGGAATTTGAACGCTTAGCCCCGCAAACCATTTATGTTTCCGCAACA
CCAGGGCCTTATGAATTAGAGAAATCAGGCTGTGAAATCATCGATCAAGTGGTTCGCCCCACTGGTTTACTTGATCCGCT
TATTGAAATTCGTCCAGTGTCAATTCAAGTGGATGATTTACTTTCCGAAGCTCGCCAAAGAGCGGATAAAAATGAACGCG
TTTTAGTGACGACGCTAACGAAGAAAATGGCTGAAGATTTAACGGATTATTTAGATGAACACGGGATTCGTGTGCGTTAT
CTACATTCTGATATTGATACCGTGGAACGCGTCGAAATTATCCGTGATTTGCGTTTAGGCGAATTTGATGTATTGGTTGG
AATTAACTTATTACGTGAAGGTTTAGATATTCCAGAAGTGTCTCTTGTGGCGATTTTAGATGCAGACAAAGAGGGCTTTT
TGCGCTCCGAACGTTCTTTAATTCAAACCATCGGTCGTGCTGCGCGAAACTTAAATGGTAAAGCGATTTTGTATGCAGAT
AGCATCACAAAATCCATGGAAAAAGCCATCACCGAAACCAATCGTCGTCGTGAAAAACAAACAAAATACAATGAAGAACA
TGGCATTGTGCCACAGGCATTAAATAAGAAAGTCGGTGAATTATTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAG
CCAATAAACAACGTGGAAAAATGGCGGCAGAAGCAACCGCACTTTATAATGCACCGAAAAATGCCAAAGAATATCAACAA
CAAATCAAAAAATTGGAACAACAAATGTATAAATTTGCGCAAGATTTGGAATTTGAAAAAGCCGCGGCTATTCGCGATCA
ATTACATCAATTGCGTGAACAATTTGTTTTTGATAACTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(164-254)

Type III restriction enzyme, res subunit (ResIII)

(20-102)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)

Ultra-violet resistance protein B (UvrB)

(557-598)

UvrB/uvrC motif (UVR)

(640-674)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.292

98.969

0.567
  uvrB Streptococcus pneumoniae R6

57.292

98.969

0.567
  uvrB Streptococcus pneumoniae D39

57.292

98.969

0.567

Multiple sequence alignment