Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ORI30_RS12570 Genome accession   NZ_CP110996
Coordinates   2616555..2617145 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain XYEH3783     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2611555..2622145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ORI30_RS12555 (ORI30_12555) uhpT 2612195..2613586 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  ORI30_RS12560 (ORI30_12560) uhpC 2613724..2615043 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  ORI30_RS12565 (ORI30_12565) uhpB 2615053..2616555 (-) 1503 WP_001314238.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  ORI30_RS12570 (ORI30_12570) letA 2616555..2617145 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  ORI30_RS12575 (ORI30_12575) ilvN 2617218..2617508 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  ORI30_RS12580 (ORI30_12580) ilvB 2617512..2619200 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  ORI30_RS12585 (ORI30_12585) ivbL 2619306..2619404 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  ORI30_RS12590 (ORI30_12590) ysdE 2619649..2619723 (-) 75 WP_211180519.1 protein YsdE -
  ORI30_RS12595 (ORI30_12595) emrD 2619805..2620989 (+) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  ORI30_RS12600 (ORI30_12600) yidF 2620997..2621494 (-) 498 WP_000148045.1 radical SAM protein -
  ORI30_RS12605 (ORI30_12605) yidG 2621491..2621853 (-) 363 WP_001113432.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=685936 ORI30_RS12570 WP_000633668.1 2616555..2617145(-) (letA) [Escherichia coli strain XYEH3783]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=685936 ORI30_RS12570 WP_000633668.1 2616555..2617145(-) (letA) [Escherichia coli strain XYEH3783]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACATGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378