Detailed information NTG0068328

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SNAG_RS01490
• Genome accession: NZ_AP017652
• Coordinates: 259952..260962 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090640.1
• Uniprot ID: A0A1E1G8V4
• Organism: Streptococcus sp. NPS 308
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 254952..265962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SNAG_RS01465 (SNAG_0294)	-	255382..256704 (+)	1323	WP_096405963.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
SNAG_RS01470 (SNAG_0295)	folE	256685..257239 (+)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
SNAG_RS01475 (SNAG_0296)	folK	257282..258103 (+)	822	WP_096405965.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
SNAG_RS01480 (SNAG_0297)	-	258096..259379 (+)	1284	WP_096405966.1	DUF308 domain-containing protein	-
SNAG_RS01485 (SNAG_0298)	-	259430..259747 (-)	318	WP_000886038.1	DUF960 domain-containing protein	-
SNAG_RS01490 (SNAG_0299)	ccpA	259952..260962 (+)	1011	WP_001090640.1	catabolite control protein A	Regulator
SNAG_RS01495 (SNAG_0300)	-	261014..261976 (-)	963	WP_096405968.1	asparaginase	-
SNAG_RS01500 (SNAG_0301)	-	262042..263427 (+)	1386	WP_000453132.1	Cof-type HAD-IIB family hydrolase	-
SNAG_RS01505 (SNAG_0302)	-	263466..263918 (-)	453	WP_000079162.1	universal stress protein	-
SNAG_RS01510 (SNAG_0303)	-	264260..265474 (+)	1215	WP_096405969.1	pyridoxal phosphate-dependent aminotransferase	-
SNAG_RS01515 (SNAG_0304)	rpmH	265619..265753 (+)	135	WP_000831905.1	50S ribosomal protein L34	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37217.28 Da
• Isoelectric Point: 5.5218

>NTDB_id=68328 SNAG_RS01490 WP_001090640.1 259952..260962(+) (ccpA) [Streptococcus sp. NPS 308]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIERLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGIPYSEGLVFESKYSYNDGYALAERLVSSQ
ATAAVVTGDELAAGVLNGLSDHGVSVPEEFEIITTDDSQIARYTRPNLTTVAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=68328 SNAG_RS01490 WP_001090640.1 259952..260962(+) (ccpA) [Streptococcus sp. NPS 308]
ATGAACACAGATGATACAGTAACGATTTATGACGTTGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTCGAAGTGATTGAACGCTTGGACTATCGTCCAAATG
CGGTCGCTCGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCTAACATTACCAATGGTTATTTCTCA
ACACTTGCTAAGGGGATTGATGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACGCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAATTCTCTCGTTCACGGACGCCGGTTGTTCTTGCAGGTACGGTGGATGTAGAACACCAACTTCCAAGT
GTGAATATTGACTACAAACAAGCCACGATTGACGCAGTGAGCTATCTTCTTAAAGAAAATGAGAAAATTGCCTTTGTGAG
TGGCCCGCTTGTCGATGATATCAATGGCAAGGTTCGTTTGATTGGTTATAAGGAAGCTTTGAAAAAAGCAGGAATCCCTT
ATAGCGAGGGCTTGGTTTTTGAATCAAAATATAGCTATAACGATGGTTATGCCTTGGCAGAACGGTTGGTTTCATCACAA
GCTACAGCTGCAGTTGTGACTGGTGACGAATTGGCAGCAGGTGTGCTAAATGGTTTATCAGATCATGGTGTTTCAGTGCC
AGAAGAGTTTGAAATCATTACGACGGATGACTCTCAAATTGCACGATACACTCGTCCAAACTTGACGACAGTTGCCCAAC
CGCTTTATGATTTGGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAATTGGAAGAGCGCGAAGTT
CTCCTACCTCATGGTTTGACAGAACGTCGTTCTACACGAAAACGCAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: A0A1E1G8V4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	92.857	100	0.929
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.61	98.512	0.577