Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   OLR76_RS19395 Genome accession   NZ_CP110017
Coordinates   3947087..3947677 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain HE_50     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3942087..3952677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OLR76_RS19380 (OLR76_19285) uhpT 3942727..3944118 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  OLR76_RS19385 (OLR76_19290) uhpC 3944256..3945575 (-) 1320 WP_241218384.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  OLR76_RS19390 (OLR76_19295) uhpB 3945585..3947087 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  OLR76_RS19395 (OLR76_19300) letA 3947087..3947677 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  OLR76_RS19400 (OLR76_19305) ilvN 3947753..3948043 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  OLR76_RS19405 (OLR76_19310) ilvB 3948047..3949735 (-) 1689 WP_282983319.1 acetolactate synthase large subunit -
  OLR76_RS19410 (OLR76_19315) ivbL 3949841..3949939 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  OLR76_RS19415 (OLR76_19320) tisB 3950504..3950593 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  OLR76_RS19420 (OLR76_19325) ysdE 3950717..3950791 (-) 75 WP_211180519.1 protein YsdE -
  OLR76_RS19425 (OLR76_19330) emrD 3950873..3952057 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  OLR76_RS19430 (OLR76_19335) yidF 3952065..3952562 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=682844 OLR76_RS19395 WP_000633668.1 3947087..3947677(-) (letA) [Escherichia coli strain HE_50]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=682844 OLR76_RS19395 WP_000633668.1 3947087..3947677(-) (letA) [Escherichia coli strain HE_50]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378