Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPATCC43504_RS01150 Genome accession   NZ_AP017632
Coordinates   244980..245717 (+) Length   245 a.a.
NCBI ID   WP_000660523.1    Uniprot ID   A0AAD1D9W4
Organism   Helicobacter pylori strain ATCC 43504     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 239980..250717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPATCC43504_RS01125 (HPATCC43504_00227) panD 242138..242491 (+) 354 WP_000142226.1 aspartate 1-decarboxylase -
  HPATCC43504_RS01130 (HPATCC43504_00228) - 242494..242796 (+) 303 WP_000347928.1 YbaB/EbfC family nucleoid-associated protein -
  HPATCC43504_RS01135 (HPATCC43504_00229) - 242796..243791 (+) 996 WP_108169555.1 PDZ domain-containing protein -
  HPATCC43504_RS01140 (HPATCC43504_00230) comB6 243799..244854 (+) 1056 WP_108169556.1 P-type conjugative transfer protein TrbL Machinery gene
  HPATCC43504_RS01145 (HPATCC43504_00231) comB7 244870..244983 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  HPATCC43504_RS01150 (HPATCC43504_00232) comB8 244980..245717 (+) 738 WP_000660523.1 virB8 family protein Machinery gene
  HPATCC43504_RS01155 (HPATCC43504_00233) comB9 245717..246697 (+) 981 WP_108169557.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPATCC43504_RS01160 (HPATCC43504_00234) comB10 246690..247826 (+) 1137 WP_108169558.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPATCC43504_RS01165 (HPATCC43504_00235) - 247897..249309 (+) 1413 WP_108169559.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPATCC43504_RS01170 (HPATCC43504_00236) gmd 249351..250496 (+) 1146 WP_111735917.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28530.74 Da        Isoelectric Point: 8.9546

>NTDB_id=68273 HPATCC43504_RS01150 WP_000660523.1 244980..245717(+) (comB8) [Helicobacter pylori strain ATCC 43504]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=68273 HPATCC43504_RS01150 WP_000660523.1 244980..245717(+) (comB8) [Helicobacter pylori strain ATCC 43504]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGTTGGAGAGAAACCGATTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCTATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGCTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.976

Multiple sequence alignment