Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   JLH08_RS03705 Genome accession   NZ_AP022540
Coordinates   781021..781680 (-) Length   219 a.a.
NCBI ID   WP_001221486.1    Uniprot ID   -
Organism   Escherichia coli strain THO-010     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 776021..786680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JLH08_RS03680 (THOESC010_07240) parE 776073..777965 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  JLH08_RS03685 (THOESC010_07250) ygiN 778013..778327 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  JLH08_RS03690 (THOESC010_07260) mdaB 778358..778939 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  JLH08_RS03695 (THOESC010_07270) ygiZ 779297..779629 (+) 333 WP_000912091.1 DUF2645 family protein -
  JLH08_RS03700 (THOESC010_07280) qseC 779675..781024 (-) 1350 WP_200930416.1 quorum sensing histidine kinase QseC -
  JLH08_RS03705 (THOESC010_07290) ciaR 781021..781680 (-) 660 WP_001221486.1 quorum sensing response regulator transcription factor QseB Regulator
  JLH08_RS03710 (THOESC010_07300) ygiW 781832..782224 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  JLH08_RS03715 (THOESC010_07310) ygiV 782277..782759 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  JLH08_RS03720 (THOESC010_07320) ygiS 782868..784475 (+) 1608 WP_040234936.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24692.61 Da        Isoelectric Point: 6.3527

>NTDB_id=68238 JLH08_RS03705 WP_001221486.1 781021..781680(-) (ciaR) [Escherichia coli strain THO-010]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=68238 JLH08_RS03705 WP_001221486.1 781021..781680(-) (ciaR) [Escherichia coli strain THO-010]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment