Detailed information NTG0068216

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: JMUB1235_RS02260
• Genome accession: NZ_AP017629
• Coordinates: 417867..418868 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain JMUB1235
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 412867..423868

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMUB1235_RS02235 (JMUB1235_0442)	-	413541..414224 (-)	684	WP_031488436.1	DUF969 domain-containing protein	-
JMUB1235_RS02240 (JMUB1235_0443)	-	414435..415361 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
JMUB1235_RS02245 (JMUB1235_0444)	-	415506..415883 (-)	378	WP_002985686.1	VOC family protein	-
JMUB1235_RS02250 (JMUB1235_0445)	-	415894..416559 (-)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
JMUB1235_RS02255 (JMUB1235_0446)	-	416608..417693 (-)	1086	WP_031488434.1	aminopeptidase P family protein	-
JMUB1235_RS02260 (JMUB1235_0447)	ccpA	417867..418868 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
JMUB1235_RS02265 (JMUB1235_0448)	-	418999..419997 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
JMUB1235_RS02270 (JMUB1235_0449)	-	419999..421333 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
JMUB1235_RS02275 (JMUB1235_0450)	thrS	421755..423698 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=68216 JMUB1235_RS02260 WP_002985680.1 417867..418868(+) (ccpA) [Streptococcus pyogenes strain JMUB1235]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=68216 JMUB1235_RS02260 WP_002985680.1 417867..418868(+) (ccpA) [Streptococcus pyogenes strain JMUB1235]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559