Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   MZN68_RS08125 Genome accession   NZ_CP096117
Coordinates   1614482..1615177 (-) Length   231 a.a.
NCBI ID   WP_002215704.1    Uniprot ID   Q7DDR6
Organism   Neisseria meningitidis strain DFS-1910310016     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1598790..1616007 1614482..1615177 within 0


Gene organization within MGE regions


Location: 1598790..1616007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MZN68_RS08030 - 1598790..1599272 (-) 483 WP_061729868.1 hypothetical protein -
  MZN68_RS08035 - 1599399..1599560 (-) 162 WP_153559544.1 hypothetical protein -
  MZN68_RS08040 (MZN68_07940) - 1600510..1600755 (-) 246 WP_002224299.1 hypothetical protein -
  MZN68_RS08045 (MZN68_07945) - 1600867..1601295 (+) 429 WP_002212270.1 CopD family protein -
  MZN68_RS08050 (MZN68_07950) - 1601307..1601783 (+) 477 WP_002224298.1 CYTH domain-containing protein -
  MZN68_RS08055 (MZN68_07955) - 1602133..1602621 (-) 489 WP_002224297.1 dihydrofolate reductase -
  MZN68_RS08060 (MZN68_07960) aroG 1602689..1603744 (-) 1056 WP_002216371.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  MZN68_RS08065 (MZN68_07965) - 1603906..1604133 (-) 228 WP_153310284.1 hypothetical protein -
  MZN68_RS08070 (MZN68_07970) - 1604356..1604664 (+) 309 WP_076612699.1 hypothetical protein -
  MZN68_RS08075 (MZN68_07975) - 1604713..1604817 (-) 105 Protein_1570 IS1595 family transposase -
  MZN68_RS08080 - 1604989..1605123 (-) 135 WP_256864600.1 hypothetical protein -
  MZN68_RS08085 (MZN68_07980) comE 1605492..1605956 (-) 465 WP_011798959.1 ComEA family DNA-binding protein Machinery gene
  MZN68_RS08115 (MZN68_08010) - 1611754..1612560 (-) 807 WP_076612651.1 inner membrane protein YpjD -
  MZN68_RS08120 (MZN68_08015) ffh 1612781..1614151 (+) 1371 WP_076612650.1 signal recognition particle protein -
  MZN68_RS08125 (MZN68_08020) dsbA2 1614482..1615177 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  MZN68_RS08130 (MZN68_08025) - 1615348..1616007 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25419.90 Da        Isoelectric Point: 5.1502

>NTDB_id=679517 MZN68_RS08125 WP_002215704.1 1614482..1615177(-) (dsbA2) [Neisseria meningitidis strain DFS-1910310016]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=679517 MZN68_RS08125 WP_002215704.1 1614482..1615177(-) (dsbA2) [Neisseria meningitidis strain DFS-1910310016]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCTGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7DDR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

100

100

1
  dsbA1 Neisseria meningitidis MC58

71.245

100

0.719