Detailed information NTG0679458

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: MZN67_RS07285
• Genome accession: NZ_CP096116
• Coordinates: 1615107..1615970 (+)
• Length: 287 a.a.
• NCBI ID: WP_014841651.1
• Uniprot ID: I7HJU7
• Organism: Legionella pneumophila subsp. pneumophila strain DFS-2111020037
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1610107..1620970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MZN67_RS07265 (MZN67_07240)	-	1610601..1610927 (-)	327	WP_011213802.1	DUF1820 family protein	-
MZN67_RS07270 (MZN67_07245)	-	1611110..1611853 (-)	744	WP_014841649.1	methyltransferase domain-containing protein	-
MZN67_RS07275 (MZN67_07250)	pilB	1612112..1613836 (+)	1725	WP_010947251.1	type IV-A pilus assembly ATPase PilB	Machinery gene
MZN67_RS07280 (MZN67_07255)	pilC	1613842..1615062 (+)	1221	WP_014841650.1	type II secretion system F family protein	Machinery gene
MZN67_RS07285 (MZN67_07260)	pilD	1615107..1615970 (+)	864	WP_014841651.1	A24 family peptidase	Machinery gene
MZN67_RS07290 (MZN67_07265)	-	1615984..1617189 (-)	1206	WP_014841652.1	cyclic nucleotide-binding domain-containing protein	-
MZN67_RS07295 (MZN67_07270)	-	1617297..1617890 (-)	594	WP_011213808.1	hypothetical protein	-
MZN67_RS07300 (MZN67_07275)	-	1617906..1618361 (-)	456	WP_014841654.1	hypothetical protein	-
MZN67_RS07305 (MZN67_07280)	-	1618495..1619310 (+)	816	WP_014841655.1	pyruvate, water dikinase regulatory protein	-
MZN67_RS07310 (MZN67_07285)	-	1619430..1620878 (-)	1449	WP_014841656.1	bifunctional 2-methylcitrate dehydratase/aconitate hydratase	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 32756.36 Da
• Isoelectric Point: 7.8442

>NTDB_id=679458 MZN67_RS07285 WP_014841651.1 1615107..1615970(+) (pilD) [Legionella pneumophila subsp. pneumophila strain DFS-2111020037]
MINALIINYPWFMYLVVGLFSLAVGSLLNVIIYRLPIILQEEWKEQCCELFHLEQRKEKIKLNLFLPRSFCPHCKAMVKA
WQNIPLLSYILLRGRCYQCDSPISIRYPFVETLTTVLSLYASWHFGFTIQLLFALLAIWILISLVFIDLDHQLLPDSLTL
GLLWIGLIANTQNVFVSLDVAVLSCAGAYLALWLFINLFYLMTGKVGMGHGDFKLFAAFGAWLGWMYLPLILLISSITGA
IIGLIYLKINGKSRDTAIPFGPFLCISGLIAMFWGDSIITWYIGYWM

Nucleotide

• Length: 864 bp

>NTDB_id=679458 MZN67_RS07285 WP_014841651.1 1615107..1615970(+) (pilD) [Legionella pneumophila subsp. pneumophila strain DFS-2111020037]
ATGATAAATGCACTAATAATCAATTATCCATGGTTTATGTATTTAGTCGTTGGACTCTTTTCTCTAGCCGTTGGAAGTTT
GCTTAATGTGATAATCTATCGCTTGCCAATTATTTTGCAGGAAGAGTGGAAAGAGCAATGCTGTGAGCTATTCCATCTTG
AACAGCGAAAAGAAAAAATAAAACTTAATTTATTTTTACCACGTTCTTTTTGTCCTCATTGTAAAGCGATGGTTAAAGCG
TGGCAGAATATTCCTCTGTTAAGCTATATTTTGTTAAGAGGACGCTGTTACCAATGTGATAGTCCAATTTCAATCCGCTA
CCCTTTTGTTGAGACGTTGACCACAGTTTTATCCTTATACGCCAGTTGGCATTTTGGGTTTACAATACAATTATTATTTG
CTTTATTAGCTATCTGGATATTAATATCACTTGTTTTTATTGATCTTGATCATCAATTACTCCCTGATAGCCTCACTTTA
GGGCTCTTATGGATTGGCCTTATTGCTAATACCCAGAATGTATTTGTTAGTCTTGACGTTGCTGTATTAAGCTGCGCTGG
CGCCTATTTAGCCTTATGGTTATTCATTAATCTGTTTTATCTGATGACAGGTAAGGTAGGTATGGGACATGGAGATTTCA
AATTATTTGCAGCATTTGGTGCCTGGCTTGGATGGATGTATTTACCATTAATTCTACTAATATCTTCAATAACGGGGGCT
ATCATTGGTTTGATTTATTTAAAGATAAATGGTAAATCAAGAGATACTGCAATACCATTTGGCCCTTTTCTTTGCATTTC
TGGATTAATAGCTATGTTTTGGGGAGACTCAATTATCACTTGGTATATAGGTTATTGGATGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (19-125)

• Type IV leader peptidase family (Peptidase_A24) (136-244)

3D structure

• AlphaFold DB: I7HJU7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	49.11	97.909	0.481
pilD	Acinetobacter nosocomialis M2	47.985	95.122	0.456
pilD	Acinetobacter baumannii D1279779	47.273	95.819	0.453
pilD	Vibrio campbellii strain DS40M4	44.964	96.864	0.436
pilD	Neisseria gonorrhoeae MS11	42.446	96.864	0.411