Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M0D62_RS09500 Genome accession   NZ_CP096114
Coordinates   1962748..1963377 (-) Length   209 a.a.
NCBI ID   WP_000153529.1    Uniprot ID   A0A7U7PW36
Organism   Staphylococcus argenteus strain MRSA-139-14-168     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1957748..1968377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0D62_RS09470 (M0D62_09460) - 1958156..1958686 (-) 531 WP_000184380.1 acyl-CoA thioesterase -
  M0D62_RS09475 (M0D62_09465) - 1958778..1960025 (-) 1248 WP_047436874.1 aminopeptidase -
  M0D62_RS09480 (M0D62_09470) - 1960037..1960237 (-) 201 WP_047436877.1 DUF1128 family protein -
  M0D62_RS09485 (M0D62_09475) - 1960384..1960848 (+) 465 WP_000228669.1 low molecular weight protein-tyrosine-phosphatase -
  M0D62_RS09490 (M0D62_09480) - 1960855..1961130 (+) 276 WP_047436880.1 YtxH domain-containing protein -
  M0D62_RS09495 (M0D62_09485) - 1961409..1962632 (+) 1224 WP_000037065.1 YihY/virulence factor BrkB family protein -
  M0D62_RS09500 (M0D62_09490) vraR 1962748..1963377 (-) 630 WP_000153529.1 two-component system response regulator VraR Regulator
  M0D62_RS09505 (M0D62_09495) vraS 1963367..1964410 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  M0D62_RS09510 (M0D62_09500) liaF 1964407..1965108 (-) 702 WP_000149061.1 cell wall-active antibiotics response protein LiaF -
  M0D62_RS09515 (M0D62_09505) - 1965123..1965509 (-) 387 WP_001110170.1 hypothetical protein -
  M0D62_RS09520 (M0D62_09510) map 1965730..1966488 (-) 759 WP_031788218.1 type I methionyl aminopeptidase -
  M0D62_RS09525 (M0D62_09515) - 1966955..1967941 (+) 987 WP_047436883.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23517.28 Da        Isoelectric Point: 5.3889

>NTDB_id=679427 M0D62_RS09500 WP_000153529.1 1962748..1963377(-) (vraR) [Staphylococcus argenteus strain MRSA-139-14-168]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSKGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=679427 M0D62_RS09500 WP_000153529.1 1962748..1963377(-) (vraR) [Staphylococcus argenteus strain MRSA-139-14-168]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTAGGTGAGGGGGCTTCAGGTAAAGAAGCAATCGCTAAAGCCCATGAGCTAAAACCTGATTTGATTTTAA
TGGATTTGCTTATGGATGATATGGATGGTGTAGAAGCGACTACTCAAATTAAAAAAGATTTACCACAAATTAAAGTATTA
ATGCTAACAAGTTTTATTGAAGATAAAGAGGTATATCGTGCCTTAGATGCAGGTGTTGATAGCTATATTTTAAAAACAAC
GAGTGCAAAAGATATTGCTGATGCAGTTCGTAAAACATCTAAAGGTGAATCTGTATTTGAACCTGAAGTATTAGTAAAAA
TGCGTAACCGTATGAAAAAACGTGCTGAGTTATATGAAATGTTAACAGAACGTGAAATGGAAATATTATTATTAATTGCC
AAAGGTTATTCAAATCAAGAAATTGCAAGTGCATCTCATATTACAATTAAAACAGTTAAGACACATGTAAGTAATATTTT
AAGTAAGTTAGAAGTACAAGATAGAACACAAGCCGTTATTTATGCATTCCAACATAATTTAATTCAGTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PW36

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373