Detailed information NTG0679428

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: M0D62_RS09505
• Genome accession: NZ_CP096114
• Coordinates: 1963367..1964410 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain MRSA-139-14-168
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1958367..1969410

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M0D62_RS09475 (M0D62_09465)	-	1958778..1960025 (-)	1248	WP_047436874.1	aminopeptidase	-
M0D62_RS09480 (M0D62_09470)	-	1960037..1960237 (-)	201	WP_047436877.1	DUF1128 family protein	-
M0D62_RS09485 (M0D62_09475)	-	1960384..1960848 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
M0D62_RS09490 (M0D62_09480)	-	1960855..1961130 (+)	276	WP_047436880.1	YtxH domain-containing protein	-
M0D62_RS09495 (M0D62_09485)	-	1961409..1962632 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
M0D62_RS09500 (M0D62_09490)	vraR	1962748..1963377 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
M0D62_RS09505 (M0D62_09495)	vraS	1963367..1964410 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
M0D62_RS09510 (M0D62_09500)	liaF	1964407..1965108 (-)	702	WP_000149061.1	cell wall-active antibiotics response protein LiaF	-
M0D62_RS09515 (M0D62_09505)	-	1965123..1965509 (-)	387	WP_001110170.1	hypothetical protein	-
M0D62_RS09520 (M0D62_09510)	map	1965730..1966488 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
M0D62_RS09525 (M0D62_09515)	-	1966955..1967941 (+)	987	WP_047436883.1	aromatic acid exporter family protein	-
M0D62_RS09530 (M0D62_09520)	-	1968345..1968725 (-)	381	WP_223804866.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=679428 M0D62_RS09505 WP_001017131.1 1963367..1964410(-) (vraS) [Staphylococcus argenteus strain MRSA-139-14-168]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=679428 M0D62_RS09505 WP_001017131.1 1963367..1964410(-) (vraS) [Staphylococcus argenteus strain MRSA-139-14-168]
ATGAACCATTATATTAGAACAATTGGTTCTATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTTGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTCTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCGTTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGACTTTAAAGTGCCAAAAGGTATTGAGGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1