Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   MUA78_RS06610 Genome accession   NZ_CP095116
Coordinates   1304884..1305858 (+) Length   324 a.a.
NCBI ID   WP_000697222.1    Uniprot ID   A0A2S6D0Y6
Organism   Staphylococcus aureus strain IVB6156     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1299884..1310858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA78_RS06575 (MUA78_06570) rpmG 1300344..1300493 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  MUA78_RS06580 (MUA78_06575) - 1300702..1301241 (+) 540 WP_000164552.1 5-formyltetrahydrofolate cyclo-ligase -
  MUA78_RS06585 (MUA78_06580) - 1301253..1302716 (+) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  MUA78_RS06590 (MUA78_06585) - 1302697..1302900 (+) 204 WP_000087561.1 YqgQ family protein -
  MUA78_RS06595 (MUA78_06590) - 1302897..1303883 (+) 987 WP_000161315.1 ROK family glucokinase -
  MUA78_RS06600 (MUA78_06595) - 1303883..1304212 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  MUA78_RS06605 (MUA78_06600) - 1304209..1304832 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  MUA78_RS06610 (MUA78_06605) comGA 1304884..1305858 (+) 975 WP_000697222.1 competence type IV pilus ATPase ComGA Machinery gene
  MUA78_RS06615 (MUA78_06610) comGB 1305830..1306900 (+) 1071 WP_262515456.1 competence type IV pilus assembly protein ComGB Machinery gene
  MUA78_RS06620 (MUA78_06615) comGC 1306914..1307225 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  MUA78_RS06625 (MUA78_06620) comGD 1307203..1307649 (+) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  MUA78_RS06630 (MUA78_06625) comGE 1307636..1307935 (+) 300 WP_029549199.1 hypothetical protein Machinery gene
  MUA78_RS06635 (MUA78_06630) comGF 1307853..1308350 (+) 498 WP_029656266.1 competence type IV pilus minor pilin ComGF Machinery gene
  MUA78_RS06640 (MUA78_06635) - 1308447..1308593 (+) 147 WP_001789879.1 hypothetical protein -
  MUA78_RS06645 (MUA78_06640) - 1308583..1309107 (+) 525 WP_001015120.1 shikimate kinase -
  MUA78_RS06650 (MUA78_06645) gcvT 1309266..1310357 (+) 1092 WP_250406248.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36874.92 Da        Isoelectric Point: 8.8508

>NTDB_id=675573 MUA78_RS06610 WP_000697222.1 1304884..1305858(+) (comGA) [Staphylococcus aureus strain IVB6156]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSNNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=675573 MUA78_RS06610 WP_000697222.1 1304884..1305858(+) (comGA) [Staphylococcus aureus strain IVB6156]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCTACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAAGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCAATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6D0Y6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997