Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   MUA78_RS06615 Genome accession   NZ_CP095116
Coordinates   1305830..1306900 (+) Length   356 a.a.
NCBI ID   WP_262515456.1    Uniprot ID   -
Organism   Staphylococcus aureus strain IVB6156     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1300830..1311900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA78_RS06585 (MUA78_06580) - 1301253..1302716 (+) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  MUA78_RS06590 (MUA78_06585) - 1302697..1302900 (+) 204 WP_000087561.1 YqgQ family protein -
  MUA78_RS06595 (MUA78_06590) - 1302897..1303883 (+) 987 WP_000161315.1 ROK family glucokinase -
  MUA78_RS06600 (MUA78_06595) - 1303883..1304212 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  MUA78_RS06605 (MUA78_06600) - 1304209..1304832 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  MUA78_RS06610 (MUA78_06605) comGA 1304884..1305858 (+) 975 WP_000697222.1 competence type IV pilus ATPase ComGA Machinery gene
  MUA78_RS06615 (MUA78_06610) comGB 1305830..1306900 (+) 1071 WP_262515456.1 competence type IV pilus assembly protein ComGB Machinery gene
  MUA78_RS06620 (MUA78_06615) comGC 1306914..1307225 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  MUA78_RS06625 (MUA78_06620) comGD 1307203..1307649 (+) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  MUA78_RS06630 (MUA78_06625) comGE 1307636..1307935 (+) 300 WP_029549199.1 hypothetical protein Machinery gene
  MUA78_RS06635 (MUA78_06630) comGF 1307853..1308350 (+) 498 WP_029656266.1 competence type IV pilus minor pilin ComGF Machinery gene
  MUA78_RS06640 (MUA78_06635) - 1308447..1308593 (+) 147 WP_001789879.1 hypothetical protein -
  MUA78_RS06645 (MUA78_06640) - 1308583..1309107 (+) 525 WP_001015120.1 shikimate kinase -
  MUA78_RS06650 (MUA78_06645) gcvT 1309266..1310357 (+) 1092 WP_250406248.1 glycine cleavage system aminomethyltransferase GcvT -
  MUA78_RS06655 (MUA78_06650) gcvPA 1310377..1311723 (+) 1347 WP_000019686.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41485.89 Da        Isoelectric Point: 10.1030

>NTDB_id=675574 MUA78_RS06615 WP_262515456.1 1305830..1306900(+) (comGB) [Staphylococcus aureus strain IVB6156]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNKFNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQSILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=675574 MUA78_RS06615 WP_262515456.1 1305830..1306900(+) (comGB) [Staphylococcus aureus strain IVB6156]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTGATTTATAACAAATTTAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAATTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGTCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.157

100

0.992
  comGB Staphylococcus aureus N315

99.157

100

0.992