Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA12_RS08635 Genome accession   NZ_CP095104
Coordinates   1688796..1689425 (-) Length   209 a.a.
NCBI ID   WP_002481662.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6179     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1683796..1694425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA12_RS08605 (MUA12_08560) - 1684265..1685503 (-) 1239 WP_107547749.1 aminopeptidase -
  MUA12_RS08610 (MUA12_08565) - 1685540..1685746 (-) 207 WP_262577061.1 DUF1128 domain-containing protein -
  MUA12_RS08615 (MUA12_08570) - 1685970..1686434 (+) 465 WP_023015860.1 low molecular weight protein-tyrosine-phosphatase -
  MUA12_RS08620 (MUA12_08575) - 1686442..1686732 (+) 291 WP_002481659.1 hypothetical protein -
  MUA12_RS08625 (MUA12_08580) - 1686863..1687939 (+) 1077 WP_105978635.1 YihY/virulence factor BrkB family protein -
  MUA12_RS08630 (MUA12_08585) - 1688147..1688725 (+) 579 WP_262577064.1 carbonic anhydrase -
  MUA12_RS08635 (MUA12_08590) vraR 1688796..1689425 (-) 630 WP_002481662.1 response regulator transcription factor Regulator
  MUA12_RS08640 (MUA12_08595) vraS 1689415..1690458 (-) 1044 WP_002481663.1 sensor histidine kinase Regulator
  MUA12_RS08645 (MUA12_08600) liaF 1690455..1691156 (-) 702 WP_002481664.1 cell wall-active antibiotics response protein LiaF -
  MUA12_RS08650 (MUA12_08605) - 1691172..1691567 (-) 396 WP_262577066.1 hypothetical protein -
  MUA12_RS08655 (MUA12_08610) map 1691683..1692447 (-) 765 WP_002481666.1 type I methionyl aminopeptidase -
  MUA12_RS08660 (MUA12_08615) - 1692667..1693653 (+) 987 WP_002481667.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23719.32 Da        Isoelectric Point: 4.6245

>NTDB_id=675471 MUA12_RS08635 WP_002481662.1 1688796..1689425(-) (vraR) [Staphylococcus simulans strain IVB6179]
MAIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELQPDLILMDLLMEDMDGVEATMQIKKDLPQIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTYRNEAVFEAEVLVKMRNRMNQRAELYELLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=675471 MUA12_RS08635 WP_002481662.1 1688796..1689425(-) (vraR) [Staphylococcus simulans strain IVB6179]
ATGGCGATTAAAGTATTATTTGTCGATGACCACGAAATGGTTCGTATCGGCATCTCAAGTTATTTATCTACACAACCTGA
TATCGAAGTCGTCGGGGAAGGCAAATCAGGTAAAGAAGCAATTGAAAAAGCTCATGAATTGCAGCCTGATTTAATCTTGA
TGGATTTGTTGATGGAAGACATGGATGGCGTAGAAGCTACAATGCAGATTAAAAAAGATTTACCTCAGATTAAAGTATTG
ATGCTGACAAGTTATATTGAGGATAATGAAGTGTATCGTGCTTTAGACGCTGGGGTAGACAGTTATATTCTAAAAACGAC
GAGCGCAAGTGATATCGCAGAAGCGATTCGTAAAACATATCGTAACGAAGCGGTGTTTGAAGCGGAAGTACTTGTTAAAA
TGCGTAATCGCATGAATCAACGTGCTGAATTATATGAATTATTAACAGATAGAGAAATGGAAATTTTATTGTTAATCGCA
AAAGGTTATTCTAACCAAGAAATCGCCAGTGCGTCACATATTACGATTAAAACAGTTAAAACACATGTGAGTAATATATT
AAGCAAGCTAGAAGTTCAAGACAGAACACAAGCTGTTATTTACGCATTCCAACACGATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368