Detailed information NTG0675472

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA12_RS08640
• Genome accession: NZ_CP095104
• Coordinates: 1689415..1690458 (-)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6179
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1684415..1695458

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA12_RS08610 (MUA12_08565)	-	1685540..1685746 (-)	207	WP_262577061.1	DUF1128 domain-containing protein	-
MUA12_RS08615 (MUA12_08570)	-	1685970..1686434 (+)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA12_RS08620 (MUA12_08575)	-	1686442..1686732 (+)	291	WP_002481659.1	hypothetical protein	-
MUA12_RS08625 (MUA12_08580)	-	1686863..1687939 (+)	1077	WP_105978635.1	YihY/virulence factor BrkB family protein	-
MUA12_RS08630 (MUA12_08585)	-	1688147..1688725 (+)	579	WP_262577064.1	carbonic anhydrase	-
MUA12_RS08635 (MUA12_08590)	vraR	1688796..1689425 (-)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA12_RS08640 (MUA12_08595)	vraS	1689415..1690458 (-)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA12_RS08645 (MUA12_08600)	liaF	1690455..1691156 (-)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA12_RS08650 (MUA12_08605)	-	1691172..1691567 (-)	396	WP_262577066.1	hypothetical protein	-
MUA12_RS08655 (MUA12_08610)	map	1691683..1692447 (-)	765	WP_002481666.1	type I methionyl aminopeptidase	-
MUA12_RS08660 (MUA12_08615)	-	1692667..1693653 (+)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA12_RS08665 (MUA12_08620)	-	1693736..1694455 (-)	720	WP_262577068.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=675472 MUA12_RS08640 WP_002481663.1 1689415..1690458(-) (vraS) [Staphylococcus simulans strain IVB6179]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=675472 MUA12_RS08640 WP_002481663.1 1689415..1690458(-) (vraS) [Staphylococcus simulans strain IVB6179]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATTTTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATCGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAATGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTATTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862