Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   JMUB0001_RS00325 Genome accession   NZ_AP014956
Coordinates   62714..64342 (-) Length   542 a.a.
NCBI ID   WP_001186596.1    Uniprot ID   -
Organism   Staphylococcus capitis strain TW2795     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 44220..65709 62714..64342 within 0


Gene organization within MGE regions


Location: 44220..65709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMUB0001_RS00205 (JMUB0001_36) mecA 44220..46229 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  JMUB0001_RS00210 (JMUB0001_37) mecR1 46326..48083 (+) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  JMUB0001_RS00215 (JMUB0001_38) mecI 48083..48454 (+) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  JMUB0001_RS12240 psm-mec 48539..48607 (-) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  JMUB0001_RS00225 (JMUB0001_40) - 48941..50071 (+) 1131 WP_010922808.1 ROK family transcriptional regulator -
  JMUB0001_RS00235 (JMUB0001_42) cstB 50185..51519 (-) 1335 Protein_41 persulfide dioxygenase-sulfurtransferase CstB -
  JMUB0001_RS00240 (JMUB0001_43) - 51552..52616 (-) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  JMUB0001_RS00245 (JMUB0001_44) cstR 52752..53012 (+) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  JMUB0001_RS00250 (JMUB0001_45) - 53012..53650 (+) 639 Protein_44 sulfite exporter TauE/SafE family protein -
  JMUB0001_RS00260 (JMUB0001_46) - 53995..54657 (-) 663 WP_001092058.1 class I SAM-dependent methyltransferase -
  JMUB0001_RS00275 (JMUB0001_47) erm(A) 55166..55897 (+) 732 WP_001072201.1 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) -
  JMUB0001_RS00280 (JMUB0001_48) - 56023..56805 (-) 783 WP_000067268.1 aminoglycoside nucleotidyltransferase ANT(9)-Ia -
  JMUB0001_RS00285 (JMUB0001_49) - 56956..57333 (-) 378 WP_000361059.1 DUF6262 family protein -
  JMUB0001_RS00290 (JMUB0001_50) - 57340..59232 (-) 1893 WP_001557544.1 site-specific integrase -
  JMUB0001_RS00295 (JMUB0001_51) - 59229..60314 (-) 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
  JMUB0001_RS00300 - 60433..60756 (-) 324 WP_000088091.1 JAB domain-containing protein -
  JMUB0001_RS00305 - 60749..60955 (-) 207 WP_001077283.1 hypothetical protein -
  JMUB0001_RS00310 (JMUB0001_52) - 60957..61478 (-) 522 WP_000836008.1 DUF1643 domain-containing protein -
  JMUB0001_RS00315 (JMUB0001_53) - 61497..61808 (-) 312 WP_000833212.1 DUF960 family protein -
  JMUB0001_RS00320 (JMUB0001_54) - 61893..62243 (-) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  JMUB0001_RS00325 (JMUB0001_55) ccrB 62714..64342 (-) 1629 WP_001186596.1 recombinase family protein Machinery gene
  JMUB0001_RS00330 (JMUB0001_56) ccrA 64363..65709 (-) 1347 WP_000816499.1 recombinase family protein Machinery gene

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62274.15 Da        Isoelectric Point: 9.7334

>NTDB_id=67525 JMUB0001_RS00325 WP_001186596.1 62714..64342(-) (ccrB) [Staphylococcus capitis strain TW2795]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=67525 JMUB0001_RS00325 WP_001186596.1 62714..64342(-) (ccrB) [Staphylococcus capitis strain TW2795]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

86.531

100

0.865

Multiple sequence alignment