Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   MP619_RS08480 Genome accession   NZ_CP095081
Coordinates   1687876..1688877 (-) Length   333 a.a.
NCBI ID   WP_003049927.1    Uniprot ID   A0A9X5LWR8
Organism   Streptococcus dysgalactiae strain WJ001     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1685173..1739591 1687876..1688877 within 0
IScluster/Tn 1685173..1689967 1687876..1688877 within 0


Gene organization within MGE regions


Location: 1685173..1739591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS08470 (MP619_08440) - 1685173..1686150 (-) 978 WP_218661298.1 IS30 family transposase -
  MP619_RS08475 (MP619_08445) - 1686259..1687722 (-) 1464 WP_129556044.1 alpha-amylase -
  MP619_RS08480 (MP619_08450) ccpA 1687876..1688877 (-) 1002 WP_003049927.1 catabolite control protein A Regulator
  MP619_RS08485 (MP619_08455) - 1688960..1689967 (-) 1008 WP_268227754.1 IS30 family transposase -
  MP619_RS08490 (MP619_08460) - 1690137..1691222 (+) 1086 WP_129556045.1 Xaa-Pro peptidase family protein -
  MP619_RS08495 (MP619_08465) - 1691267..1691932 (+) 666 WP_129556046.1 NAD(P)H-dependent oxidoreductase -
  MP619_RS08500 (MP619_08470) - 1691942..1692319 (+) 378 WP_003049924.1 VOC family protein -
  MP619_RS08505 (MP619_08475) - 1692666..1693850 (+) 1185 WP_012766664.1 DNA/RNA non-specific endonuclease -
  MP619_RS08510 (MP619_08480) - 1693987..1694913 (+) 927 WP_129556047.1 glycosyltransferase family 2 protein -
  MP619_RS08525 (MP619_08495) - 1697637..1697813 (-) 177 WP_231112790.1 hypothetical protein -
  MP619_RS08530 (MP619_08500) smpB 1698166..1698633 (-) 468 WP_129556050.1 SsrA-binding protein SmpB -
  MP619_RS08535 (MP619_08505) rnr 1698636..1700966 (-) 2331 WP_172595997.1 ribonuclease R -
  MP619_RS08540 (MP619_08510) secG 1701063..1701299 (-) 237 WP_003047129.1 preprotein translocase subunit SecG -
  MP619_RS08545 (MP619_08515) rpmG 1701345..1701491 (-) 147 WP_003047126.1 50S ribosomal protein L33 -
  MP619_RS08550 (MP619_08520) - 1701488..1702704 (-) 1217 Protein_1639 multidrug efflux MFS transporter -
  MP619_RS08555 (MP619_08525) - 1702868..1704370 (-) 1503 WP_129556052.1 helicase HerA-like domain-containing protein -
  MP619_RS08560 (MP619_08530) - 1704481..1705164 (-) 684 WP_231112791.1 hypothetical protein -
  MP619_RS08570 (MP619_08540) - 1706316..1707341 (-) 1026 WP_231112792.1 hypothetical protein -
  MP619_RS08575 (MP619_08545) - 1707331..1708032 (-) 702 WP_129556059.1 ABC transporter ATP-binding protein -
  MP619_RS08580 (MP619_08550) coaE 1708485..1709096 (-) 612 WP_281429820.1 dephospho-CoA kinase -
  MP619_RS08585 (MP619_08555) mutM 1709075..1709902 (-) 828 WP_129556057.1 DNA-formamidopyrimidine glycosylase -
  MP619_RS08590 (MP619_08560) - 1709914..1710072 (-) 159 WP_003049903.1 hypothetical protein -
  MP619_RS08595 (MP619_08565) rgg2 1710084..1710938 (-) 855 WP_129556401.1 quorum-sensing system transcriptional regulator Rgg2 -
  MP619_RS08600 (MP619_08570) shp2 1711027..1711095 (+) 69 WP_134771781.1 peptide pheromone SHP2 -
  MP619_RS08605 (MP619_08575) - 1711164..1712765 (+) 1602 WP_268227755.1 transglutaminase domain-containing protein -
  MP619_RS08610 (MP619_08580) - 1712803..1713081 (+) 279 WP_129556055.1 StcA family protein -
  MP619_RS08615 (MP619_08585) - 1713109..1714028 (-) 920 Protein_1652 hypothetical protein -
  MP619_RS08620 (MP619_08590) - 1714246..1714548 (-) 303 WP_129556399.1 CPBP family intramembrane glutamic endopeptidase -
  MP619_RS08625 (MP619_08595) - 1714522..1714769 (-) 248 Protein_1654 hypothetical protein -
  MP619_RS08635 (MP619_08605) - 1716055..1716881 (-) 827 Protein_1656 IS3-like element IS981 family transposase -
  MP619_RS08640 (MP619_08610) - 1717013..1717807 (-) 795 WP_115256695.1 replication initiation protein -
  MP619_RS08645 (MP619_08615) - 1718233..1718682 (+) 450 WP_136118840.1 hypothetical protein -
  MP619_RS08650 (MP619_08620) - 1718699..1718986 (+) 288 WP_129556054.1 bacteriocin immunity protein -
  MP619_RS08655 (MP619_08625) - 1719609..1719857 (+) 249 WP_012477809.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  MP619_RS08660 (MP619_08630) - 1719857..1720174 (+) 318 WP_115256692.1 type II toxin-antitoxin system RelE/ParE family toxin -
  MP619_RS08670 (MP619_08640) - 1722573..1723310 (+) 738 Protein_1663 IS3 family transposase -
  MP619_RS08675 (MP619_08645) - 1723456..1724004 (-) 549 WP_231112795.1 hypothetical protein -
  MP619_RS08680 (MP619_08650) - 1724001..1724699 (-) 699 WP_231112796.1 hypothetical protein -
  MP619_RS08685 (MP619_08655) - 1724966..1725439 (-) 474 WP_268227756.1 NUDIX domain-containing protein -
  MP619_RS08690 (MP619_08660) era 1725626..1726522 (-) 897 WP_003047080.1 GTPase Era -
  MP619_RS08695 (MP619_08665) - 1726642..1727049 (-) 408 WP_003054389.1 diacylglycerol kinase -
  MP619_RS08700 (MP619_08670) ybeY 1727030..1727527 (-) 498 WP_003049887.1 rRNA maturation RNase YbeY -
  MP619_RS08705 (MP619_08675) - 1727686..1728261 (-) 576 WP_129556061.1 uracil-DNA glycosylase family protein -
  MP619_RS08710 (MP619_08680) - 1728308..1729369 (-) 1062 WP_129556062.1 PhoH family protein -
  MP619_RS08715 (MP619_08685) - 1729530..1731302 (-) 1773 WP_129556063.1 oleate hydratase -
  MP619_RS08720 (MP619_08690) - 1731613..1732833 (-) 1221 WP_129556064.1 LysM domain-containing protein -
  MP619_RS08725 (MP619_08695) - 1732973..1733188 (-) 216 WP_129556065.1 YozE family protein -
  MP619_RS08730 (MP619_08700) msrA 1733185..1733694 (-) 510 WP_129556066.1 peptide-methionine (S)-S-oxide reductase MsrA -
  MP619_RS08735 (MP619_08705) cvfB 1733766..1734623 (-) 858 WP_129556067.1 RNA-binding virulence regulatory protein CvfB -
  MP619_RS08740 (MP619_08710) frr 1734743..1735300 (-) 558 WP_111715585.1 ribosome recycling factor -
  MP619_RS08745 (MP619_08715) pyrH 1735328..1736056 (-) 729 WP_003049878.1 UMP kinase -
  MP619_RS08750 (MP619_08720) - 1736338..1736868 (+) 531 WP_129556068.1 hypothetical protein -
  MP619_RS08755 (MP619_08725) rplA 1737145..1737834 (-) 690 WP_003049876.1 50S ribosomal protein L1 -
  MP619_RS08760 (MP619_08730) rplK 1737940..1738365 (-) 426 WP_003049875.1 50S ribosomal protein L11 -
  MP619_RS08765 (MP619_08735) - 1738563..1739585 (-) 1023 WP_129555386.1 IS30 family transposase -

Sequence

Protein


Download         Length: 333 a.a.        Molecular weight: 36683.74 Da        Isoelectric Point: 5.7248

>NTDB_id=675107 MP619_RS08480 WP_003049927.1 1687876..1688877(-) (ccpA) [Streptococcus dysgalactiae strain WJ001]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPIVLAGTVDLDHQLPS
VNIDYKAAVSNVVDILAENHQSIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide


Download         Length: 1002 bp        

>NTDB_id=675107 MP619_RS08480 WP_003049927.1 1687876..1688877(-) (ccpA) [Streptococcus dysgalactiae strain WJ001]
ATGAATACAGATGATACCATCACGATTTATGACGTTGCCCGTGAAGCTGGTGTTTCTATGGCAACTGTTAGTCGTGTTGT
TAATGGCAACAAAAACGTTAAGGAAAACACGCGTAAGAAAGTTTTAGAAGTCATTGACCGCCTAGATTATCGTCCAAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAAACAACAACCGTCGGGGTTGTGATTCCGAATATTGCAAACAGTTATTTTTCT
ATTTTAGCCAAAGGTATTGATGATATCGCCGCTATGTATAAATATAATATTGTACTTGCCTCTAGTGATGAGGATGATGA
CAAGGAGGTTAACGTTGTCAATACCCTCTTTGCTAAGCAAGTTGACGGTATTATCTTTATGGGGCACCATTTGACTGAAA
AAATCCGTGCGGAATTTTCACGCTCACGCACCCCGATTGTTTTAGCAGGGACAGTTGACCTTGATCATCAATTACCAAGT
GTTAATATTGACTATAAGGCAGCTGTGTCTAATGTGGTTGATATTTTGGCAGAAAACCATCAGAGCATTGCCTTTGTGTC
AGGACCACTTATTGATGACATCAATGGTAAAGTACGTTTGGCGGGGTACAAAGAAGGCTTGAAGCACAACAAACTTGACT
TCAAAGAAGGACTTGTTTTTGAAGCTAACTATTCTTATAAAGAAGGCTTTGAATTGGCACAACGTGTGATTAACTCAGGA
GCAACAGCAGCTTATGTGGCTGAAGATGAGTTAGCAGCGGGTCTTTTAAATGGTTTGTTTGAAGCAGGCAAACGCGTTCC
AGAAGATTTTGAAATCATCACAAGCAATGATTCACCAGTTGTTCAATATACCCGTCCAAACTTGAGTTCTATCAGCCAAC
CCGTTTACGACTTGGGAGCTGTCAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGCGGAACCACTAAATAG

Domains

Predicted by InterproScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(177-332)

Bacterial regulatory proteins, lacI family (LacI)

(8-53)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus gordonii str. Challis substr. CH1

77.778

100

0.778
  ccpA Streptococcus pneumoniae D39

75.976

100

0.76
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

55.589

99.399

0.553