Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA21_RS08190 Genome accession   NZ_CP094825
Coordinates   1646214..1646843 (-) Length   209 a.a.
NCBI ID   WP_019469616.1    Uniprot ID   A0A6N7XUN7
Organism   Staphylococcus ureilyticus strain IVB6236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641214..1651843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA21_RS08160 (MUA21_08130) - 1641735..1642256 (-) 522 WP_262561033.1 acyl-CoA thioesterase -
  MUA21_RS08165 (MUA21_08135) - 1642407..1643645 (-) 1239 WP_107525762.1 aminopeptidase -
  MUA21_RS08170 (MUA21_08140) - 1643660..1643863 (-) 204 WP_046207949.1 DUF1128 family protein -
  MUA21_RS08175 (MUA21_08145) - 1643996..1644460 (+) 465 WP_046207950.1 low molecular weight protein-tyrosine-phosphatase -
  MUA21_RS08180 (MUA21_08150) - 1644468..1644752 (+) 285 WP_262561046.1 YtxH domain-containing protein -
  MUA21_RS08185 (MUA21_08155) - 1645056..1646144 (+) 1089 WP_262561047.1 YihY/virulence factor BrkB family protein -
  MUA21_RS08190 (MUA21_08160) vraR 1646214..1646843 (-) 630 WP_019469616.1 response regulator transcription factor Regulator
  MUA21_RS08195 (MUA21_08165) vraS 1646833..1647876 (-) 1044 WP_046207953.1 sensor histidine kinase Regulator
  MUA21_RS08200 (MUA21_08170) liaF 1647873..1648574 (-) 702 WP_073345877.1 cell wall-active antibiotics response protein LiaF -
  MUA21_RS08205 (MUA21_08175) - 1648591..1648977 (-) 387 WP_019469613.1 hypothetical protein -
  MUA21_RS08210 (MUA21_08180) map 1649082..1649834 (-) 753 WP_107525763.1 type I methionyl aminopeptidase -
  MUA21_RS08215 (MUA21_08185) - 1650011..1650997 (+) 987 WP_064209717.1 aromatic acid exporter family protein -
  MUA21_RS08220 (MUA21_08190) - 1651082..1651807 (-) 726 WP_046207957.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23774.31 Da        Isoelectric Point: 4.7152

>NTDB_id=673489 MUA21_RS08190 WP_019469616.1 1646214..1646843(-) (vraR) [Staphylococcus ureilyticus strain IVB6236]
MPIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGQSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYRDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNVLSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=673489 MUA21_RS08190 WP_019469616.1 1646214..1646843(-) (vraR) [Staphylococcus ureilyticus strain IVB6236]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAAATGGTCAGAATTGGTATTTCTAGTTATTTATCTACTCAACCAGA
TATAGAAGTAGTCGGAGAAGGGCAATCGGGGAAAGATGCAATTGAAAAAGCACATGAACTTAAGCCTGATTTAATTTTAA
TGGACTTACTCATGGATGATATGGATGGTGTAGAAGCTACAGAACAAATCAAGAAAGATTTGCCACACATTAAAGTTGTT
ATGCTAACCAGTTATATTGAAGATAATGAAGTATACCGTGCTTTAGATTCTGGTGTAGATAGTTATATTTTAAAAACGAC
AAGTGCTAGCGATATCGCCGAAGCGATACGTAAAACATATCGTGATGAATCTGTGTTTGAAGCAGAAGTGTTGGTTAAGA
TGAGGAATCGTATGAAACAACGCGCTGAATTATATGAGATGTTAACTGAACGTGAGATGGAGATATTATTATTAATCGCT
AAAGGTTACTCAAATCAGGAAATTGCTAGTGCTTCACATATTACAATCAAAACAGTTAAAACACATGTTAGTAACGTGTT
GAGTAAATTAGAAGTACAAGATAGAACTCAAGCTGTAATTTATGCATTTCAACATAATTTAATACAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N7XUN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364