Detailed information NTG0673490

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA21_RS08195
• Genome accession: NZ_CP094825
• Coordinates: 1646833..1647876 (-)
• Length: 347 a.a.
• NCBI ID: WP_046207953.1
• Uniprot ID: A0A9Q2L749
• Organism: Staphylococcus ureilyticus strain IVB6236
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1641833..1652876

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA21_RS08165 (MUA21_08135)	-	1642407..1643645 (-)	1239	WP_107525762.1	aminopeptidase	-
MUA21_RS08170 (MUA21_08140)	-	1643660..1643863 (-)	204	WP_046207949.1	DUF1128 family protein	-
MUA21_RS08175 (MUA21_08145)	-	1643996..1644460 (+)	465	WP_046207950.1	low molecular weight protein-tyrosine-phosphatase	-
MUA21_RS08180 (MUA21_08150)	-	1644468..1644752 (+)	285	WP_262561046.1	YtxH domain-containing protein	-
MUA21_RS08185 (MUA21_08155)	-	1645056..1646144 (+)	1089	WP_262561047.1	YihY/virulence factor BrkB family protein	-
MUA21_RS08190 (MUA21_08160)	vraR	1646214..1646843 (-)	630	WP_019469616.1	response regulator transcription factor	Regulator
MUA21_RS08195 (MUA21_08165)	vraS	1646833..1647876 (-)	1044	WP_046207953.1	sensor histidine kinase	Regulator
MUA21_RS08200 (MUA21_08170)	liaF	1647873..1648574 (-)	702	WP_073345877.1	cell wall-active antibiotics response protein LiaF	-
MUA21_RS08205 (MUA21_08175)	-	1648591..1648977 (-)	387	WP_019469613.1	hypothetical protein	-
MUA21_RS08210 (MUA21_08180)	map	1649082..1649834 (-)	753	WP_107525763.1	type I methionyl aminopeptidase	-
MUA21_RS08215 (MUA21_08185)	-	1650011..1650997 (+)	987	WP_064209717.1	aromatic acid exporter family protein	-
MUA21_RS08220 (MUA21_08190)	-	1651082..1651807 (-)	726	WP_046207957.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39974.35 Da
• Isoelectric Point: 5.8518

>NTDB_id=673490 MUA21_RS08195 WP_046207953.1 1646833..1647876(-) (vraS) [Staphylococcus ureilyticus strain IVB6236]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRLKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLKAPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EDFDVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=673490 MUA21_RS08195 WP_046207953.1 1646833..1647876(-) (vraS) [Staphylococcus ureilyticus strain IVB6236]
ATGAATCACTATATAAGAGCAATAGGGTCGATGTTGATATTAGTTTATAGTACATTTTTCGCTATGTTTTTTATAGATAA
AGTATTTGTGAATATTATATATTTTCAAGGTATGATTTATACACAAATCTTTGGTATTCCAGTTTTACTATTTATTAATT
TATTAGTTATATTACTATGCATCATAGTTGGCTCAGTATTAGCATATAAAATCAACCAACAAAATCATTGGTTACAAGAT
CAAATTGAACGTTCTATTGAAGGACAAACAGTTGGTATCAACGACCAGAATATAGAATTATATAATGAAACAATTGAATT
ATATCAAACACTTGTACCGCTCAATCAAGAAGTTCATAAATTACGTTTAAAAACACAAAATTTAACGAATGAATCATATA
ATATGAACGATGTGAAAGTTAAAAAAATAATTGAAGATGAAAGGCAAAGACTGGCTCGTGAGTTACATGATTCCGTAAGC
CAGCAACTATTTGCAGCAAGCATGATGCTCTCTGCTATTAAAGAAACTGATTTGAAAGCACCTTTAGATCAACAAATTCC
AGTATTGGAAAAAATGGTCCAAGATTCACAATTAGAAATGCGCGCCTTGCTATTACATTTAAGACCAATTGGCTTGAAGG
ATAAATCACTTGGTCAAGGTATCAAAGATTTAGTAGTTGATCTACAGAAAAAAGTGCCAATGAAAGTCGTACATGATATT
GAAGATTTCGACGTTCCTAAAGGCATTGAAGATCATTTGTTTAGAATTACACAAGAAGCAATTTCAAATACATTAAGACA
TTCAAAAGGTACAAAAGTTACAATTGAATTGTTTAATAGAGAGGAATATTTATTATTACGTATACAAGATGATGGTAAAG
GCTTTAACGTTGATGATAAGGTAGAACAAAGCTATGGGTTAAAAAATATGCGTGAACGAGCACTTGAAATTGGCGCAACA
TTTCATATAGTATCACTGCCAGATTCAGGAACACGGATTGAAGTCAAAGCCCCATTAAATAAGGAGGATTCGTATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.32	100	0.873