Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA52_RS04405 Genome accession   NZ_CP094814
Coordinates   934761..935390 (+) Length   209 a.a.
NCBI ID   WP_037566926.1    Uniprot ID   -
Organism   Staphylococcus agnetis strain IVB6175     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 929761..940390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA52_RS04375 (MUA52_04370) - 930082..931107 (-) 1026 WP_105995642.1 aromatic acid exporter family protein -
  MUA52_RS04380 (MUA52_04375) - 931227..931601 (-) 375 WP_262619206.1 YkvA family protein -
  MUA52_RS04385 (MUA52_04380) map 931774..932532 (+) 759 WP_105995644.1 type I methionyl aminopeptidase -
  MUA52_RS04390 (MUA52_04385) - 932631..933017 (+) 387 WP_262619207.1 hypothetical protein -
  MUA52_RS04395 (MUA52_04390) liaF 933030..933731 (+) 702 WP_103345097.1 cell wall-active antibiotics response protein LiaF -
  MUA52_RS04400 (MUA52_04395) vraS 933728..934771 (+) 1044 WP_262619208.1 sensor histidine kinase Regulator
  MUA52_RS04405 (MUA52_04400) vraR 934761..935390 (+) 630 WP_037566926.1 response regulator transcription factor Regulator
  MUA52_RS04410 (MUA52_04405) - 935458..936027 (-) 570 WP_037566924.1 carbonic anhydrase -
  MUA52_RS04415 (MUA52_04410) - 936063..937334 (-) 1272 WP_037566922.1 YihY/virulence factor BrkB family protein -
  MUA52_RS04420 (MUA52_04415) - 937450..937725 (-) 276 WP_037566921.1 hypothetical protein -
  MUA52_RS04425 (MUA52_04420) - 937733..938191 (-) 459 WP_060551426.1 low molecular weight protein-tyrosine-phosphatase -
  MUA52_RS04430 (MUA52_04425) - 938324..938533 (+) 210 WP_037566916.1 DUF1128 domain-containing protein -
  MUA52_RS04435 (MUA52_04430) - 938550..939785 (+) 1236 WP_262619209.1 aminopeptidase -
  MUA52_RS04440 (MUA52_04435) - 939799..940317 (+) 519 WP_262619210.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23591.31 Da        Isoelectric Point: 5.1805

>NTDB_id=673131 MUA52_RS04405 WP_037566926.1 934761..935390(+) (vraR) [Staphylococcus agnetis strain IVB6175]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAISKAHELKPDLILMDLVMTDMDGVEATTQIKKELPRIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSAKDIAEAIRKTFQGESVFEAEVLVKMRNRMRQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=673131 MUA52_RS04405 WP_037566926.1 934761..935390(+) (vraR) [Staphylococcus agnetis strain IVB6175]
ATGACAATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGAATTTCGAGTTATCTTTCTACACAACCAGA
CATTGAAGTAGTAGGTGAAGGGGCGTCAGGTAAAGAGGCAATCTCAAAAGCACATGAACTGAAACCGGATTTAATTTTAA
TGGATTTAGTGATGACAGATATGGATGGGGTTGAGGCTACGACACAAATTAAAAAAGAGTTACCACGTATCAAAGTGGTG
ATGCTTACAAGTTACATTGAGGATAAAGAAGTTTATCGCGCTTTAGATGCCGGTGTCGACAGCTATATTTTAAAAACAAC
AAGTGCAAAAGATATTGCCGAAGCTATTCGTAAAACATTCCAAGGCGAATCTGTTTTTGAAGCAGAAGTATTAGTGAAAA
TGCGAAATCGTATGCGACAAAGAGCTGAACTTTACGAATTGTTAACGGAACGTGAAATGGAAATTTTATTGTTGATTTCC
AAAGGGTATTCGAATCAAGAAATTGCGAGCGCTTCACATATTACGATTAAGACTGTAAAAACTCATGTGAGTAATATTTT
AAGTAAATTGGAAGTTCAGGACCGTACTCAGGCTGTGATCTATGCCTTCCAACATGGTTTAATAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383