Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA95_RS04425 Genome accession   NZ_CP094809
Coordinates   940881..941510 (+) Length   209 a.a.
NCBI ID   WP_037566926.1    Uniprot ID   -
Organism   Staphylococcus agnetis strain IVB6197     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 935881..946510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA95_RS04395 (MUA95_04385) - 936202..937227 (-) 1026 WP_105995642.1 FUSC family protein -
  MUA95_RS04400 (MUA95_04390) - 937347..937721 (-) 375 WP_262626732.1 YkvA family protein -
  MUA95_RS04405 (MUA95_04395) map 937894..938652 (+) 759 WP_105995644.1 type I methionyl aminopeptidase -
  MUA95_RS04410 (MUA95_04400) - 938751..939137 (+) 387 WP_262619207.1 hypothetical protein -
  MUA95_RS04415 (MUA95_04405) liaF 939150..939851 (+) 702 WP_103345097.1 cell wall-active antibiotics response protein LiaF -
  MUA95_RS04420 (MUA95_04410) vraS 939848..940891 (+) 1044 WP_262619208.1 sensor histidine kinase Regulator
  MUA95_RS04425 (MUA95_04415) vraR 940881..941510 (+) 630 WP_037566926.1 response regulator transcription factor Regulator
  MUA95_RS04430 (MUA95_04420) - 941577..942146 (-) 570 WP_037566924.1 beta-class carbonic anhydrase -
  MUA95_RS04435 (MUA95_04425) - 942182..943453 (-) 1272 WP_037566922.1 YihY/virulence factor BrkB family protein -
  MUA95_RS04440 (MUA95_04430) - 943569..943844 (-) 276 WP_262626733.1 YtxH domain-containing protein -
  MUA95_RS04445 (MUA95_04435) - 943852..944310 (-) 459 WP_262626734.1 low molecular weight protein-tyrosine-phosphatase -
  MUA95_RS04450 (MUA95_04440) - 944443..944652 (+) 210 WP_262626735.1 DUF1128 domain-containing protein -
  MUA95_RS04455 (MUA95_04445) - 944669..945904 (+) 1236 WP_262619209.1 aminopeptidase -
  MUA95_RS04460 (MUA95_04450) - 945918..946436 (+) 519 WP_262626736.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23591.31 Da        Isoelectric Point: 5.1805

>NTDB_id=673006 MUA95_RS04425 WP_037566926.1 940881..941510(+) (vraR) [Staphylococcus agnetis strain IVB6197]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAISKAHELKPDLILMDLVMTDMDGVEATTQIKKELPRIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSAKDIAEAIRKTFQGESVFEAEVLVKMRNRMRQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=673006 MUA95_RS04425 WP_037566926.1 940881..941510(+) (vraR) [Staphylococcus agnetis strain IVB6197]
ATGACAATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGAATTTCGAGTTATCTTTCTACACAACCAGA
CATTGAAGTAGTAGGTGAAGGGGCGTCAGGTAAAGAGGCAATCTCAAAAGCACATGAACTGAAACCGGATTTAATTTTAA
TGGATTTAGTGATGACAGATATGGATGGGGTTGAGGCTACGACACAAATTAAAAAAGAGTTACCACGTATCAAAGTGGTG
ATGCTTACAAGTTACATTGAGGATAAAGAAGTTTATCGCGCTTTAGATGCCGGTGTCGACAGCTATATTTTAAAAACAAC
AAGTGCAAAAGATATTGCCGAAGCTATTCGTAAAACATTCCAAGGTGAATCTGTTTTTGAAGCAGAAGTATTAGTGAAAA
TGCGAAATCGTATGCGACAAAGAGCTGAACTTTACGAATTGTTAACGGAACGTGAAATGGAAATTTTATTATTGATTTCC
AAAGGGTATTCGAATCAAGAAATTGCGAGCGCTTCACATATTACGATTAAGACTGTAAAAACTCATGTGAGTAATATTTT
AAGTAAATTGGAAGTTCAGGACCGTACTCAGGCTGTGATCTATGCCTTCCAACATGGTTTAATAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383