Detailed information NTG0673005

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA95_RS04420
• Genome accession: NZ_CP094809
• Coordinates: 939848..940891 (+)
• Length: 347 a.a.
• NCBI ID: WP_262619208.1
• Uniprot ID: -
• Organism: Staphylococcus agnetis strain IVB6197
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 934848..945891

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA95_RS04390 (MUA95_04380)	-	935358..936089 (+)	732	WP_262626731.1	type 1 glutamine amidotransferase	-
MUA95_RS04395 (MUA95_04385)	-	936202..937227 (-)	1026	WP_105995642.1	FUSC family protein	-
MUA95_RS04400 (MUA95_04390)	-	937347..937721 (-)	375	WP_262626732.1	YkvA family protein	-
MUA95_RS04405 (MUA95_04395)	map	937894..938652 (+)	759	WP_105995644.1	type I methionyl aminopeptidase	-
MUA95_RS04410 (MUA95_04400)	-	938751..939137 (+)	387	WP_262619207.1	hypothetical protein	-
MUA95_RS04415 (MUA95_04405)	liaF	939150..939851 (+)	702	WP_103345097.1	cell wall-active antibiotics response protein LiaF	-
MUA95_RS04420 (MUA95_04410)	vraS	939848..940891 (+)	1044	WP_262619208.1	sensor histidine kinase	Regulator
MUA95_RS04425 (MUA95_04415)	vraR	940881..941510 (+)	630	WP_037566926.1	response regulator transcription factor	Regulator
MUA95_RS04430 (MUA95_04420)	-	941577..942146 (-)	570	WP_037566924.1	beta-class carbonic anhydrase	-
MUA95_RS04435 (MUA95_04425)	-	942182..943453 (-)	1272	WP_037566922.1	YihY/virulence factor BrkB family protein	-
MUA95_RS04440 (MUA95_04430)	-	943569..943844 (-)	276	WP_262626733.1	YtxH domain-containing protein	-
MUA95_RS04445 (MUA95_04435)	-	943852..944310 (-)	459	WP_262626734.1	low molecular weight protein-tyrosine-phosphatase	-
MUA95_RS04450 (MUA95_04440)	-	944443..944652 (+)	210	WP_262626735.1	DUF1128 domain-containing protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39946.01 Da
• Isoelectric Point: 4.9468

>NTDB_id=673005 MUA95_RS04420 WP_262619208.1 939848..940891(+) (vraS) [Staphylococcus agnetis strain IVB6197]
MNQYVRSIGSMLILVYSLFTAFFFIDNVFTNIIFFQGMFYTQIFGIPVFLFLNLITIFLCIIVGSILAYKNNQQNDWLKV
QIERAIEGETVGVNDQQIEIYQETLELYEALVPLNQELHRMRIKTQNLTNESYNINDSKVQKIIEDERHRLARELHDSVS
QQLFAASMMLSAIKETPLEPPLNQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIQSLVTELKRKVPLKVVQDI
GEFDVPKGMEDHLFRITQEAISNTLRHSKGTEVTVELLQREDYILLRIQDDGIGFNVDDKMEQSYGLKNMRERAMEIGAT
FHIVSLPDSGTRIEVKAPLDKEGHNDN

Nucleotide

• Length: 1044 bp

>NTDB_id=673005 MUA95_RS04420 WP_262619208.1 939848..940891(+) (vraS) [Staphylococcus agnetis strain IVB6197]
ATGAATCAATACGTACGATCGATAGGTTCAATGCTTATTCTAGTGTATAGCTTATTTACAGCTTTCTTTTTTATAGACAA
TGTATTTACGAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTTGGTATACCTGTCTTTCTGTTTTTAAATC
TTATTACCATATTTTTGTGTATTATTGTTGGAAGTATACTTGCATATAAAAATAATCAACAAAATGATTGGCTTAAAGTT
CAAATTGAACGTGCGATTGAAGGGGAAACCGTTGGTGTAAATGATCAACAAATTGAAATTTACCAAGAAACACTAGAGCT
TTACGAAGCACTCGTGCCACTGAATCAAGAGTTACATCGCATGCGTATTAAAACGCAAAATTTAACGAATGAATCGTATA
ATATCAATGATTCAAAAGTACAAAAAATTATTGAGGATGAACGTCATCGACTTGCTAGAGAACTTCATGACAGTGTGTCA
CAACAATTGTTTGCGGCAAGTATGATGCTTTCTGCAATTAAAGAAACACCTTTAGAACCCCCATTAAATCAACAAATTCC
GACGCTTGAAAAAATGGTGCAAGATTCACAATTAGAAATGCGCGCGCTGTTATTACATTTAAGACCGATAGGCTTGAAAG
ATAAATCATTAGGTGAAGGTATTCAATCTTTAGTGACGGAGTTAAAACGTAAAGTTCCATTGAAAGTAGTTCAAGATATC
GGTGAGTTTGATGTGCCTAAGGGAATGGAAGATCATTTATTTAGAATTACACAAGAAGCGATTTCTAATACACTCCGTCA
TTCAAAAGGGACTGAAGTGACGGTGGAATTGTTACAACGAGAAGATTACATATTGCTACGCATTCAAGATGATGGTATCG
GATTTAATGTTGATGATAAGATGGAACAAAGTTATGGATTGAAAAATATGCGTGAACGTGCAATGGAAATTGGCGCGACA
TTTCATATCGTATCATTACCGGATTCAGGTACTCGAATTGAAGTGAAAGCACCATTAGATAAGGAGGGACATAATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (250-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	81.268	100	0.813