Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA37_RS04675 Genome accession   NZ_CP094803
Coordinates   977363..977992 (+) Length   209 a.a.
NCBI ID   WP_002509181.1    Uniprot ID   A0A7V7SP96
Organism   Staphylococcus arlettae strain IVB6235     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 972363..982992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA37_RS04650 (MUA37_04645) - 973222..974208 (-) 987 WP_135024393.1 aromatic acid exporter family protein -
  MUA37_RS04655 (MUA37_04650) map 974374..975126 (+) 753 WP_262624861.1 type I methionyl aminopeptidase -
  MUA37_RS04660 (MUA37_04655) - 975229..975615 (+) 387 WP_002509178.1 hypothetical protein -
  MUA37_RS04665 (MUA37_04660) liaF 975632..976333 (+) 702 WP_002509179.1 cell wall-active antibiotics response protein LiaF -
  MUA37_RS04670 (MUA37_04665) vraS 976330..977373 (+) 1044 WP_002509180.1 sensor histidine kinase Regulator
  MUA37_RS04675 (MUA37_04670) vraR 977363..977992 (+) 630 WP_002509181.1 response regulator transcription factor Regulator
  MUA37_RS04680 (MUA37_04675) - 978053..979132 (-) 1080 WP_142019533.1 YihY/virulence factor BrkB family protein -
  MUA37_RS04685 (MUA37_04680) - 979412..979696 (-) 285 WP_002509183.1 hypothetical protein -
  MUA37_RS04690 (MUA37_04685) - 979703..980167 (-) 465 WP_002509184.1 low molecular weight protein-tyrosine-phosphatase -
  MUA37_RS04695 (MUA37_04690) - 980303..980506 (+) 204 WP_142019535.1 DUF1128 family protein -
  MUA37_RS04700 (MUA37_04695) - 980518..981756 (+) 1239 WP_112369296.1 aminopeptidase -
  MUA37_RS04705 (MUA37_04700) - 981796..982317 (+) 522 WP_002509187.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23587.12 Da        Isoelectric Point: 4.7606

>NTDB_id=672909 MUA37_RS04675 WP_002509181.1 977363..977992(+) (vraR) [Staphylococcus arlettae strain IVB6235]
MPIKVLFVDDHEMVRIGISSYLSTQQDIEVVGEGKSGNEAIELAHKLQPDLILMDLVMDDMDGVDATAQVKKDLPQIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAVRKTYHGEAVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=672909 MUA37_RS04675 WP_002509181.1 977363..977992(+) (vraR) [Staphylococcus arlettae strain IVB6235]
ATGCCAATTAAAGTATTATTTGTAGATGACCATGAAATGGTTCGTATTGGAATTTCTAGTTATTTATCAACACAACAAGA
TATAGAAGTAGTAGGCGAAGGTAAGTCAGGTAATGAAGCAATTGAATTAGCACATAAGTTACAACCCGATTTAATATTAA
TGGATTTAGTTATGGATGATATGGATGGGGTAGATGCAACTGCGCAAGTAAAAAAAGACTTACCGCAAATTAAAGTAGTT
ATGTTAACAAGTTATATAGAAGATAATGAAGTATATCGTGCGTTAGATTCAGGTGTAGATAGCTATATTTTAAAAACTAC
AAGTGCAAGTGATATTGCCGAAGCGGTGCGTAAGACATATCATGGTGAGGCTGTGTTTGAAGCAGAAGTATTAGTGAAAA
TGCGTAATCGTATGAAACAACGTGCTGAGCTTTATGAGATGTTGACAGAGCGAGAGATGGAAATATTATTGTTAATTGCT
AAAGGTTATTCTAACCAAGAAATTGCTAGCGCATCACACATTACTATTAAAACAGTTAAAACACACGTAAGTAATATATT
AAGTAAATTAGAAGTACAAGACCGTACACAAGCAGTAATCTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7V7SP96

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368