Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA58_RS04125 Genome accession   NZ_CP094729
Coordinates   897275..897991 (-) Length   238 a.a.
NCBI ID   WP_262615081.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain IVB6210     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 892275..902991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA58_RS04110 (MUA58_04105) - 893556..894509 (+) 954 WP_099606347.1 LacI family DNA-binding transcriptional regulator -
  MUA58_RS04115 (MUA58_04110) - 894769..896241 (+) 1473 WP_262615079.1 sucrose-6-phosphate hydrolase -
  MUA58_RS04120 (MUA58_04115) - 896248..897207 (+) 960 WP_002457913.1 carbohydrate kinase -
  MUA58_RS04125 (MUA58_04120) agrA 897275..897991 (-) 717 WP_262615081.1 quorum-sensing response regulator AgrA Regulator
  MUA58_RS04130 (MUA58_04125) agrC 898008..899297 (-) 1290 WP_237621429.1 quorum-sensing sensor histidine kinase AgrC -
  MUA58_RS04135 (MUA58_04130) agrD 899324..899464 (-) 141 WP_002497212.1 cyclic lactone autoinducer peptide AgrD -
  MUA58_RS04140 (MUA58_04135) - 899448..900032 (-) 585 WP_262615082.1 accessory gene regulator AgrB -
  MUA58_RS04145 (MUA58_04140) hld 900349..900426 (+) 78 WP_002494082.1 delta-hemolysin -
  MUA58_RS04150 (MUA58_04145) - 900807..901592 (-) 786 WP_262615083.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27952.03 Da        Isoelectric Point: 5.6250

>NTDB_id=671455 MUA58_RS04125 WP_262615081.1 897275..897991(-) (agrA) [Staphylococcus epidermidis strain IVB6210]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELALLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=671455 MUA58_RS04125 WP_262615081.1 897275..897991(-) (agrA) [Staphylococcus epidermidis strain IVB6210]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCTTCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACTGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.975

100

0.87
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374