Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA17_RS04775 Genome accession   NZ_CP094725
Coordinates   1029066..1029695 (+) Length   209 a.a.
NCBI ID   WP_103207605.1    Uniprot ID   A0A2K3ZIJ2
Organism   Staphylococcus felis strain IVB6254     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1024066..1034695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA17_RS04745 (MUA17_04750) - 1024177..1024902 (+) 726 WP_103207595.1 type 1 glutamine amidotransferase -
  MUA17_RS04750 (MUA17_04755) - 1024982..1025980 (-) 999 WP_115856683.1 aromatic acid exporter family protein -
  MUA17_RS04755 (MUA17_04760) map 1026077..1026838 (+) 762 WP_115856682.1 type I methionyl aminopeptidase -
  MUA17_RS04760 (MUA17_04765) - 1026933..1027322 (+) 390 WP_115856681.1 hypothetical protein -
  MUA17_RS04765 (MUA17_04770) liaF 1027335..1028036 (+) 702 WP_103207601.1 cell wall-active antibiotics response protein LiaF -
  MUA17_RS04770 (MUA17_04775) vraS 1028033..1029076 (+) 1044 WP_103207603.1 sensor histidine kinase Regulator
  MUA17_RS04775 (MUA17_04780) vraR 1029066..1029695 (+) 630 WP_103207605.1 response regulator Regulator
  MUA17_RS04780 (MUA17_04785) - 1029782..1030354 (-) 573 WP_103207607.1 carbonic anhydrase -
  MUA17_RS04785 (MUA17_04790) - 1030385..1031608 (-) 1224 WP_262633090.1 YihY/virulence factor BrkB family protein -
  MUA17_RS04790 (MUA17_04795) - 1031971..1032258 (-) 288 WP_103207611.1 YtxH domain-containing protein -
  MUA17_RS04795 (MUA17_04800) - 1032260..1032724 (-) 465 WP_262633091.1 low molecular weight protein-tyrosine-phosphatase -
  MUA17_RS04800 (MUA17_04805) - 1032859..1033068 (+) 210 WP_262633092.1 DUF1128 domain-containing protein -
  MUA17_RS04805 (MUA17_04810) - 1033086..1034327 (+) 1242 WP_262633093.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23518.22 Da        Isoelectric Point: 4.8838

>NTDB_id=671355 MUA17_RS04775 WP_103207605.1 1029066..1029695(+) (vraR) [Staphylococcus felis strain IVB6254]
MTIRVLFVDDHEMVRIGISSYLSTQPDIEVVGEGESGKDAIEKAKLLKPDLILMDLVMTDMDGVEATTYIKKEMPQIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIASAIRKTSQGESVFEAEVLVKMRNRMKQRAELYELLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=671355 MUA17_RS04775 WP_103207605.1 1029066..1029695(+) (vraR) [Staphylococcus felis strain IVB6254]
ATGACAATTAGAGTATTATTTGTAGATGATCATGAAATGGTTCGTATTGGGATATCAAGTTACTTATCAACTCAACCTGA
TATAGAAGTAGTTGGTGAAGGGGAGTCGGGCAAAGATGCTATCGAAAAAGCAAAACTGTTAAAGCCTGATTTGATCTTAA
TGGATTTAGTGATGACTGACATGGATGGTGTCGAGGCAACGACTTATATTAAAAAGGAAATGCCGCAGATTAAAGTAGTC
ATGCTGACAAGCTATATAGAAGATAAAGAGGTGTATCGCGCGCTTGATGCGGGTGTTGATAGTTATATCTTAAAAACGAC
AAGTGCAAGTGATATTGCGTCAGCTATTCGTAAAACGAGTCAAGGTGAATCTGTTTTTGAAGCGGAAGTCCTCGTTAAAA
TGAGAAATCGTATGAAACAAAGAGCTGAATTGTATGAGTTGTTAACTGAAAGAGAAATGGAAATATTATTATTAATTGCC
AAGGGATATTCTAATCAGGAGATAGCAAGTGCATCACATATTACCATAAAGACCGTTAAAACACATGTTAGTAATATATT
GAGTAAGTTGGAAGTACAAGACCGTACTCAAGCAGTCATTTACGCATTTCAGCACGGATTAATCGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K3ZIJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.995

100

0.89
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368